2-((1-(1-(4-Chlorophenyl)cyclobutyl)-3-methylbutyl)amino)ethyl propionate

Base Information

Chemical Name:2-((1-(1-(4-Chlorophenyl)cyclobutyl)-3-methylbutyl)amino)ethyl propionate
CAS No.:1354280-74-2
Molecular Formula:C₂₀H₃₀ClNO₂
Molecular Weight:351.917
Hs Code.:

Synonyms:2-((1-(1-(4-Chlorophenyl)cyclobutyl)-3-methylbutyl)amino)ethyl propionate

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Chemical Property of 2-((1-(1-(4-Chlorophenyl)cyclobutyl)-3-methylbutyl)amino)ethyl propionate

Chemical Property:

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Technology Process of 2-((1-(1-(4-Chlorophenyl)cyclobutyl)-3-methylbutyl)amino)ethyl propionate

There total 2 articles about 2-((1-(1-(4-Chlorophenyl)cyclobutyl)-3-methylbutyl)amino)ethyl propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 1354282-06-6
2-(((4-Nitrophenyl)sulfonyl)oxy)ethyl propionate

: 106650-56-0,84467-54-9
didesmethylsibutramine

: 1354280-74-2
2-((1-(1-(4-Chlorophenyl)cyclobutyl)-3-methylbutyl)amino)ethyl propionate

Guidance literature:: didesmethylsibutramine; With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

2-(((4-Nitrophenyl)sulfonyl)oxy)ethyl propionate; In N,N-dimethyl-formamide; for 0.0833333h;

Reference yield:

: 28049-61-8
1-(4-chlorophenyl)cyclobutanecarbonitrile

: 1354280-74-2
2-((1-(1-(4-Chlorophenyl)cyclobutyl)-3-methylbutyl)amino)ethyl propionate

Guidance literature:: Multi-step reaction with 2 steps

1.1: toluene; diethyl ether / 18 h / 0 - 92 °C / Inert atmosphere

1.2: 0 °C

2.1: caesium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C

2.2: 0.08 h

With caesium carbonate; In diethyl ether; N,N-dimethyl-formamide; toluene;