4-bromophenyl N-bis(dimethylamino)methylene-N'-phenylcarbamimidothioate

Base Information

• Chemical Name: 4-bromophenyl N-bis(dimethylamino)methylene-N'-phenylcarbamimidothioate
• CAS No.: 1564286-33-4
• Molecular Formula: C₁₈H₂₁BrN₄S
• Molecular Weight: 405.362
• Mol file: 1564286-33-4.mol

Synonyms:4-bromophenyl N-bis(dimethylamino)methylene-N'-phenylcarbamimidothioate

Chemical Property of 4-bromophenyl N-bis(dimethylamino)methylene-N'-phenylcarbamimidothioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-bromophenyl N-bis(dimethylamino)methylene-N'-phenylcarbamimidothioate

There total 3 articles about 4-bromophenyl N-bis(dimethylamino)methylene-N'-phenylcarbamimidothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

1,4-bromoiodobenzene (589-87-7) + C12H18N4S (84764-54-5) → 4-bromophenyl N-bis(dimethylamino)methylene-N'-phenylcarbamimidothioate (1564286-33-4)

Guidance literature:

With copper(l) iodide; 1,10-Phenanthroline; potassium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 10h; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.01.006

Reference yield:

phenyl isothiocyanate (103-72-0) → 4-bromophenyl N-bis(dimethylamino)methylene-N'-phenylcarbamimidothioate (1564286-33-4)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 0.5 h

2: copper(l) iodide; 1,10-Phenanthroline; potassium carbonate / N,N-dimethyl-formamide / 10 h / 110 °C / Inert atmosphere

With copper(l) iodide; 1,10-Phenanthroline; potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1016/j.tetlet.2014.01.006

Reference yield:

N,N,N',N'-tetramethylguanidine (80-70-6) → 4-bromophenyl N-bis(dimethylamino)methylene-N'-phenylcarbamimidothioate (1564286-33-4)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 0.5 h

2: copper(l) iodide; 1,10-Phenanthroline; potassium carbonate / N,N-dimethyl-formamide / 10 h / 110 °C / Inert atmosphere

With copper(l) iodide; 1,10-Phenanthroline; potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1016/j.tetlet.2014.01.006

upstream raw materials:

N,N,N',N'-tetramethylguanidine

1,4-bromoiodobenzene

C₁₂H₁₈N₄S

phenyl isothiocyanate