benzyl (3S,5S,6S)-2-<<2-<<(benzyloxy)carbonyl>amino>ethyl>thio>-6-<(R)-1-hydroxyethyl>carbapen-1-em-3-carboxylate

Base Information

• Chemical Name: benzyl (3S,5S,6S)-2-<<2-<<(benzyloxy)carbonyl>amino>ethyl>thio>-6-<(R)-1-hydroxyethyl>carbapen-1-em-3-carboxylate
• CAS No.: 70382-78-4
• Molecular Formula: C₂₆H₂₈N₂O₆S
• Molecular Weight: 496.584

Synonyms:benzyl (3S,5S,6S)-2-<<2-<<(benzyloxy)carbonyl>amino>ethyl>thio>-6-<(R)-1-hydroxyethyl>carbapen-1-em-3-carboxylate

Chemical Property of benzyl (3S,5S,6S)-2-<<2-<<(benzyloxy)carbonyl>amino>ethyl>thio>-6-<(R)-1-hydroxyethyl>carbapen-1-em-3-carboxylate

Chemical Property:

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Technology Process of benzyl (3S,5S,6S)-2-<<2-<<(benzyloxy)carbonyl>amino>ethyl>thio>-6-<(R)-1-hydroxyethyl>carbapen-1-em-3-carboxylate

There total 2 articles about benzyl (3S,5S,6S)-2-<<2-<<(benzyloxy)carbonyl>amino>ethyl>thio>-6-<(R)-1-hydroxyethyl>carbapen-1-em-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

N-<(benzyloxy)carbonyl>thienamycin benzyl ester (64067-12-5) → benzyl (3S,5S,6S)-2-<<2-<<(benzyloxy)carbonyl>amino>ethyl>thio>-6-<(R)-1-hydroxyethyl>carbapen-1-em-3-carboxylate (70382-78-4)

Guidance literature:

With 1,5-Diazabicyclo[5.4.0]undec-5-ene; In dimethyl sulfoxide; for 0.166667h; Ambient temperature;

DOI:10.1021/jm00137a032

Reference yield:

→ 3-(2-Benzyloxycarbonylamino-ethylsulfanyl)-6-(1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-3-ene-2-carboxylic acid benzyl ester (70382-78-4)

Guidance literature:

entspr. Δ²-Verb.;

upstream raw materials:

N-<(benzyloxy)carbonyl>thienamycin benzyl ester

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