1-(2-chloro-5-(methylthio)phenyl)-3-(3-(difluoromethoxy)phenyl)-1-methylguanidine

Base Information

Chemical Name:1-(2-chloro-5-(methylthio)phenyl)-3-(3-(difluoromethoxy)phenyl)-1-methylguanidine
CAS No.:1415399-33-5
Molecular Formula:C₁₆H₁₆ClF₂N₃OS
Molecular Weight:371.838
Hs Code.:

Synonyms:1-(2-chloro-5-(methylthio)phenyl)-3-(3-(difluoromethoxy)phenyl)-1-methylguanidine

Suppliers and Price of 1-(2-chloro-5-(methylthio)phenyl)-3-(3-(difluoromethoxy)phenyl)-1-methylguanidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(2-chloro-5-(methylthio)phenyl)-3-(3-(difluoromethoxy)phenyl)-1-methylguanidine

Chemical Property:

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Technology Process of 1-(2-chloro-5-(methylthio)phenyl)-3-(3-(difluoromethoxy)phenyl)-1-methylguanidine

There total 2 articles about 1-(2-chloro-5-(methylthio)phenyl)-3-(3-(difluoromethoxy)phenyl)-1-methylguanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: N-methyl-(2-chloro-5-methylthio)aniline hydrochloride

: 1415399-72-2
N-(3-(difluoromethoxy)phenyl)cyanamide

: 1415399-33-5
1-(2-chloro-5-(methylthio)phenyl)-3-(3-(difluoromethoxy)phenyl)-1-methylguanidine

Guidance literature:: In chlorobenzene; Inert atmosphere; Heating;
DOI:10.1016/j.bmc.2014.12.029

Reference yield:

: 22236-08-4
3-[(difluoromethyl)oxy]aniline

: 1415399-33-5
1-(2-chloro-5-(methylthio)phenyl)-3-(3-(difluoromethoxy)phenyl)-1-methylguanidine

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether / 0 - 20 °C

2: chlorobenzene / Inert atmosphere; Heating

In diethyl ether; chlorobenzene;
DOI:10.1016/j.bmc.2014.12.029