3-amino-5-oxo-4-(p-chlorophenyl)-2-carbamoyl-4,10-dihydroindeno<1',2':6,5>pyrido<2,3-b>thiophene

Base Information

Chemical Name:3-amino-5-oxo-4-(p-chlorophenyl)-2-carbamoyl-4,10-dihydroindeno<1',2':6,5>pyrido<2,3-b>thiophene
CAS No.:127870-97-7
Molecular Formula:C₂₁H₁₄ClN₃O₂S
Molecular Weight:407.88
Hs Code.:

Synonyms:3-amino-5-oxo-4-(p-chlorophenyl)-2-carbamoyl-4,10-dihydroindeno<1',2':6,5>pyrido<2,3-b>thiophene

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Chemical Property of 3-amino-5-oxo-4-(p-chlorophenyl)-2-carbamoyl-4,10-dihydroindeno<1',2':6,5>pyrido<2,3-b>thiophene

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Technology Process of 3-amino-5-oxo-4-(p-chlorophenyl)-2-carbamoyl-4,10-dihydroindeno<1',2':6,5>pyrido<2,3-b>thiophene

There total 2 articles about 3-amino-5-oxo-4-(p-chlorophenyl)-2-carbamoyl-4,10-dihydroindeno<1',2':6,5>pyrido<2,3-b>thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 127871-14-1
2-[4-(4-Chloro-phenyl)-3-cyano-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridin-2-ylsulfanyl]-acetamide

: 127870-97-7
3-amino-5-oxo-4-(p-chlorophenyl)-2-carbamoyl-4,10-dihydroindeno<1',2':6,5>pyrido<2,3-b>thiophene

Guidance literature:: With sodium hydroxide; In ethanol; a) reflux, 3-5 min, b) r.t., 30 min;
DOI:10.1007/BF00506858

Reference yield:

: 15875-54-4
2-(4-chlorobenzylidene)-2H-indene-1,3-dione

: 127870-97-7
3-amino-5-oxo-4-(p-chlorophenyl)-2-carbamoyl-4,10-dihydroindeno<1',2':6,5>pyrido<2,3-b>thiophene

Guidance literature:: Multi-step reaction with 2 steps

2: 90 percent / 3 N NaOH / ethanol / a) reflux, 3-5 min, b) r.t., 30 min

With sodium hydroxide; In ethanol;
DOI:10.1007/BF00506858