cis-4-(3-(2-Fluoroethyl)-3-nitrosoureido)cyclohexanecarboxylic acid

Base Information

Chemical Name:cis-4-(3-(2-Fluoroethyl)-3-nitrosoureido)cyclohexanecarboxylic acid
CAS No.:61137-52-8
Molecular Formula:C₁₀H₁₆FN₃O₄
Molecular Weight:261.253
Hs Code.:
NSC Number:224094,224092
DSSTox Substance ID:DTXSID80976653
Nikkaji Number:J75.375K,J75.376I
ChEMBL ID:CHEMBL2051751,CHEMBL2051942

Synonyms:61137-62-0;61137-52-8;NSC 224094;NSC 224092;4-({[(2-fluoroethyl)(nitroso)amino]carbonyl}amino)cyclohexanecarboxylic acid;cis-4-(3-(2-Fluoroethyl)-3-nitrosoureido)cyclohexanecarboxylic acid;trans-3-(4-Carboxycyclohexyl)-1-(2-fluoroethyl)-1-nitrosourea;trans-4-(3-(2-Fluoroethyl)-3-nitrosoureido)cyclohexanecarboxylic acid;Urea, 3-(4-carboxycyclohexyl)-1-(2-fluoroethyl)-1-nitroso-, (E)-;CHEMBL2051751;CHEMBL2051942;DTXSID80976653;NSC224092;NSC224094;Cyclohexanecarboxylic acid, 4-(3-(2-fluoroethyl)-3-nitrosoureido)-, (E)-;Cyclohexanecarboxylic acid, 4-(3-(2-fluoroethyl)-3-nitrosoureido)-, (Z)-;NSC-224092;NSC-224094;Cyclohexanecarboxylic acid, 4-((((2-fluoroethyl)nitrosoamino)carbonyl)amino)-, cis-;Cyclohexanecarboxylic acid, 4-((((2-fluoroethyl)nitrosoamino)carbonyl)amino)-, trans-;4-({[(2-Fluoroethyl)(nitroso)amino](hydroxy)methylidene}amino)cyclohexane-1-carboxylic acid

Suppliers and Price of cis-4-(3-(2-Fluoroethyl)-3-nitrosoureido)cyclohexanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of cis-4-(3-(2-Fluoroethyl)-3-nitrosoureido)cyclohexanecarboxylic acid

Chemical Property:

Density:1.47g/cm³
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:261.11248416
Heavy Atom Count:18
Complexity:318

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(CCC1C(=O)O)NC(=O)N(CCF)N=O

Technology Process of cis-4-(3-(2-Fluoroethyl)-3-nitrosoureido)cyclohexanecarboxylic acid

There total 3 articles about cis-4-(3-(2-Fluoroethyl)-3-nitrosoureido)cyclohexanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 61367-06-4
4-[3-(2-Fluoro-ethyl)-ureido]-cyclohexanecarboxylic acid

: 61137-52-8
C₁₀H₁₆FN₃O₄

Guidance literature:: With formic acid; sodium nitrite;
DOI:10.1021/jm00212a019

Reference yield:

: 61367-05-3
4-[3-(2-Chloro-ethyl)-ureido]-cyclohexanecarboxylic acid

: 61137-52-8
C₁₀H₁₆FN₃O₄

Guidance literature:: Multi-step reaction with 3 steps

1: NaNO₂, HCO₂H

2: Et₃N

3: NaNO₂, HCO₂H

With formic acid; triethylamine; sodium nitrite;
DOI:10.1021/jm00212a019

Reference yield:

: 42558-94-1
C₁₀H₁₆ClN₃O₄

: 61137-52-8
C₁₀H₁₆FN₃O₄

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N

2: NaNO₂, HCO₂H

With formic acid; triethylamine; sodium nitrite;
DOI:10.1021/jm00212a019