2S-[2R,3R-bisbenzyloxy-3R-methyl-5R-(triisopropylsilanyloxy)-tetrahydropyran-4-yloxy]-4-{3S-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanoxy)-tetrahydropyran-2R-ylmethyl]-2S-methyl-oxiranyl}butyraldehyde

Base Information

Chemical Name:2S-[2R,3R-bisbenzyloxy-3R-methyl-5R-(triisopropylsilanyloxy)-tetrahydropyran-4-yloxy]-4-{3S-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanoxy)-tetrahydropyran-2R-ylmethyl]-2S-methyl-oxiranyl}butyraldehyde
CAS No.:569661-73-0
Molecular Formula:C₅₇H₉₄O₁₃Si₂
Molecular Weight:1043.54
Hs Code.:

2S-[2R,3R-bisbenzyloxy-3R-methyl-5R-(triisopropylsilanyloxy)-tetrahydropyran-4-yloxy]-4-{3S-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanoxy)-tetrahydropyran-2R-ylmethyl]-2S-methyl-oxiranyl}butyraldehyde

Synonyms:2S-[2R,3R-bisbenzyloxy-3R-methyl-5R-(triisopropylsilanyloxy)-tetrahydropyran-4-yloxy]-4-{3S-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanoxy)-tetrahydropyran-2R-ylmethyl]-2S-methyl-oxiranyl}butyraldehyde

Suppliers and Price of 2S-[2R,3R-bisbenzyloxy-3R-methyl-5R-(triisopropylsilanyloxy)-tetrahydropyran-4-yloxy]-4-{3S-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanoxy)-tetrahydropyran-2R-ylmethyl]-2S-methyl-oxiranyl}butyraldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2S-[2R,3R-bisbenzyloxy-3R-methyl-5R-(triisopropylsilanyloxy)-tetrahydropyran-4-yloxy]-4-{3S-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanoxy)-tetrahydropyran-2R-ylmethyl]-2S-methyl-oxiranyl}butyraldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2S-[2R,3R-bisbenzyloxy-3R-methyl-5R-(triisopropylsilanyloxy)-tetrahydropyran-4-yloxy]-4-{3S-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanoxy)-tetrahydropyran-2R-ylmethyl]-2S-methyl-oxiranyl}butyraldehyde

There total 7 articles about 2S-[2R,3R-bisbenzyloxy-3R-methyl-5R-(triisopropylsilanyloxy)-tetrahydropyran-4-yloxy]-4-{3S-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanoxy)-tetrahydropyran-2R-ylmethyl]-2S-methyl-oxiranyl}butyraldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 569661-71-8
2-(2,3-bis-benzyloxy-3-methyl-5-triisopropylsilanyloxy-tetrahydro-pyran-4-yloxy)-4-{3-[6-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4-methoxymethoxy-3-triethylsilanyloxy-tetrahydro-pyran-2-ylmethyl]-2-methyl-oxiranyl}-butan-1-ol

: 569661-73-0
2S-[2R,3R-bisbenzyloxy-3R-methyl-5R-(triisopropylsilanyloxy)-tetrahydropyran-4-yloxy]-4-{3S-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanoxy)-tetrahydropyran-2R-ylmethyl]-2S-methyl-oxiranyl}butyraldehyde

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at -78 - 0 ℃;
DOI:10.1021/ja029225v

Reference yield:

: 80522-42-5
triisopropylsilyl trifluoromethanesulfonate

: 569661-73-0
2S-[2R,3R-bisbenzyloxy-3R-methyl-5R-(triisopropylsilanyloxy)-tetrahydropyran-4-yloxy]-4-{3S-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanoxy)-tetrahydropyran-2R-ylmethyl]-2S-methyl-oxiranyl}butyraldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: 92 percent / 2,6-lutidine / various solvent(s) / 0.25 h / -78 °C

2: CH₂Cl₂; methanol / 25 h / -30 °C

3: LiAlH₄ / tetrahydrofuran / 0.75 h / -78 °C

4: oxalyl chloride; dimethylsulfoxide; diisopropylethylamine / CH₂Cl₂ / -78 - 0 °C

With 2,6-dimethylpyridine; lithium aluminium tetrahydride; oxalyl dichloride; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; dichloromethane; 4: Swern oxidation;
DOI:10.1021/ja029225v

Reference yield:

: 569661-02-5
7R,8R-dibenzyloxy-2S-{5-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanyloxy)-tetrahydropyran-2R-yl]-3-methylpent-3E-enyl}-8R-methyltetrahydropyrano[3R,4R-b][1,4]dioxin-3-one

: 569661-73-0
2S-[2R,3R-bisbenzyloxy-3R-methyl-5R-(triisopropylsilanyloxy)-tetrahydropyran-4-yloxy]-4-{3S-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanoxy)-tetrahydropyran-2R-ylmethyl]-2S-methyl-oxiranyl}butyraldehyde

Guidance literature:: Multi-step reaction with 6 steps

1: aq. lithium hydroxide / tetrahydrofuran / 0.33 h / 0 °C

2: 2.57 g / 2,6-lutidine; N-iodosuccinimide / CH₂Cl₂ / 3.5 h / 0 - 20 °C

3: 92 percent / 2,6-lutidine / various solvent(s) / 0.25 h / -78 °C

4: CH₂Cl₂; methanol / 25 h / -30 °C

5: LiAlH₄ / tetrahydrofuran / 0.75 h / -78 °C

6: oxalyl chloride; dimethylsulfoxide; diisopropylethylamine / CH₂Cl₂ / -78 - 0 °C

With 2,6-dimethylpyridine; lithium hydroxide; N-iodo-succinimide; lithium aluminium tetrahydride; oxalyl dichloride; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; dichloromethane; 6: Swern oxidation;
DOI:10.1021/ja029225v