2-(4-nitrobenzylidene)cyclopentanone

Base Information

• Chemical Name: 2-(4-nitrobenzylidene)cyclopentanone
• CAS No.: 71496-93-0
• Molecular Formula: C12H11NO3
• Molecular Weight: 217.224
• Mol file: 71496-93-0.mol

Synonyms:

Chemical Property of 2-(4-nitrobenzylidene)cyclopentanone

Chemical Property:

• Vapor Pressure: 1.02E-05mmHg at 25°C
• Boiling Point: 371.6°C at 760 mmHg
• Flash Point: 179.9°C
• Density: 1.317g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-nitrobenzylidene)cyclopentanone

There total 5 articles about 2-(4-nitrobenzylidene)cyclopentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-nitrobenzaldehdye (555-16-8) + 2-ethoxycarbonyl-1-cyclopentanone (611-10-9) → 2-(4-nitrobenzylidene)cyclopentanone (71496-93-0)

Guidance literature:

With aniline; In water; acetonitrile; at 30 ℃; for 12h; Enzymatic reaction;

DOI:10.1039/b914653a

Reference yield: 84.0%

4-nitrobenzaldehdye (555-16-8) + cyclopentanone (120-92-3) → 2-(4-nitrobenzylidene)cyclopentanone (71496-93-0)

Guidance literature:

With pyrrolidine; for 0.0666667h; chemoselective reaction; Sonication; Inert atmosphere;

DOI:10.1016/j.ultsonch.2012.11.004

Reference yield:

4-[5-(4-nitrobenzyliden)-1-cyclopenten-1-yl]morpholine (588699-52-9) → 2-(4-nitrobenzylidene)cyclopentanone (71496-93-0)

Guidance literature:

With hydrogenchloride; In toluene; for 1h;

DOI:10.1039/b711620a

upstream raw materials:

1-cyclopentenyloxy-diethylaminochloroborane

4-nitrobenzaldehdye

cyclopentanone

4-[5-(4-nitrobenzyliden)-1-cyclopenten-1-yl]morpholine

Downstream raw materials:

C₁₃H₁₄N₄O₂S

Refernces

• 1、 Mojtahedi, Mohammad M.,Abaee, M. Saeed,Samianifard, Mehdieh,Shamloo, Akram,Padyab, Masoomeh,Mesbah, A. Wahid,Harms, Klaus. "Ultrasound mediation for efficient synthesis of monoarylidene derivatives of homo- and heterocyclic ketones". . p. 924 - 930. Retrieved 2013/03/13.
• 2、 Austin, Mark,Egan, Oliver J.,Tully, Raymond,Pratt, Albert C.. "Quinoline synthesis: Scope and regiochemistry of photocyclisation of substituted benzylidenecyclopentanone O-alkyl and O-acetyloximes". . p. 3778 - 3786. Retrieved 2008/10/09.