2-pyridinecarboxylic acid, heptyl ester

Base Information

• Chemical Name: 2-pyridinecarboxylic acid, heptyl ester
• CAS No.: 100618-66-4
• Molecular Formula: C₁₃H₁₉NO₂
• Molecular Weight: 221.299
• Mol file: 100618-66-4.mol

Synonyms:pyridine-2-carboxylic acid heptyl ester

Chemical Property of 2-pyridinecarboxylic acid, heptyl ester

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-pyridinecarboxylic acid, heptyl ester

There total 2 articles about 2-pyridinecarboxylic acid, heptyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-Cyanopyridine (100-70-9,1232006-36-8) + n-heptan1ol (111-70-6) → pyridine-2-carboxylic acid amide (1452-77-3) + pyridine-2-carboxylic acid heptyl ester (100618-66-4)

Guidance literature:

With cerium(IV) oxide; water; In o-xylene; at 160 ℃; for 26h; Inert atmosphere;

DOI:10.1021/acscatal.6b00272

Reference yield:

2-hydroxyiminomethyl-pyridine (2110-14-7) → pyridine-2-carboxylic acid amide (1452-77-3) + pyridine-2-carboxylic acid heptyl ester (100618-66-4)

Guidance literature:

Multi-step reaction with 2 steps

1: cerium(IV) oxide / o-xylene / 6 h / 160 °C / Dean-Stark; Inert atmosphere

2: cerium(IV) oxide; water / o-xylene / 26 h / 160 °C / Inert atmosphere

With cerium(IV) oxide; water; In o-xylene;

DOI:10.1021/acscatal.6b00272

upstream raw materials:

2-Cyanopyridine

n-heptan1ol

2-hydroxyiminomethyl-pyridine

Refernces