2-phenylmalonic acid mono-tert-butyl ester monochloride

Base Information

Chemical Name:2-phenylmalonic acid mono-tert-butyl ester monochloride
CAS No.:57079-57-9
Molecular Formula:C₁₃H₁₅ClO₃
Molecular Weight:254.713
Hs Code.:

Synonyms:2-phenylmalonic acid mono-tert-butyl ester monochloride

Suppliers and Price of 2-phenylmalonic acid mono-tert-butyl ester monochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-phenylmalonic acid mono-tert-butyl ester monochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-phenylmalonic acid mono-tert-butyl ester monochloride

There total 1 articles about 2-phenylmalonic acid mono-tert-butyl ester monochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 55610-35-0
phenylmalonic acid tert-butyl ethyl ester

: 57079-57-9
2-phenylmalonic acid mono-tert-butyl ester monochloride

Guidance literature:: With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/acs.orglett.8b03214

Reference yield:

: 57079-57-9
2-phenylmalonic acid mono-tert-butyl ester monochloride

: 536-74-3
phenylacetylene

: tert-butyl-3-hydroxy-2,5-diphenylpent-2-en-4-ynoate

Guidance literature:: phenylacetylene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.25h; Inert atmosphere;

2-phenylmalonic acid mono-tert-butyl ester monochloride; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;
DOI:10.1021/acs.orglett.8b03214

Reference yield:

: 57079-57-9
2-phenylmalonic acid mono-tert-butyl ester monochloride

: 766-97-2
4-n-methylphenylacetylene

: tert-butyl-3-hydroxy-2-phenyl-5-(p-tolyl)pent-2-en-4-ynoate

Guidance literature:: 4-n-methylphenylacetylene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1.5h; Inert atmosphere;

2-phenylmalonic acid mono-tert-butyl ester monochloride; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/acs.orglett.8b03214