C₂₅H₃₃N₃O₃

Base Information

• Chemical Name: C₂₅H₃₃N₃O₃
• CAS No.: 1447826-05-2
• Molecular Formula: C₂₅H₃₃N₃O₃
• Molecular Weight: 423.555
• Mol file: 1447826-05-2.mol

Synonyms:C₂₅H₃₃N₃O₃

Chemical Property of C₂₅H₃₃N₃O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₃₃N₃O₃

There total 14 articles about C₂₅H₃₃N₃O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C30H41N3O5 (1447825-79-7) → C25H33N3O3 (1447826-05-2)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1021/jm400542h

Reference yield:

C33H39NO4Si (1447825-68-4) → C25H33N3O3 (1447826-05-2)

Guidance literature:

Multi-step reaction with 12 steps

1.1: diisobutylaluminium hydride / dichloromethane; toluene / 0.33 h / -78 °C

1.2: 1 h / 20 °C

2.1: copper(II) sulfate / dichloromethane / 22 h / 20 °C

3.1: tetrahydrofuran; dichloromethane / 0.67 h / 20 °C

4.1: hydrogenchloride / methanol; ethyl acetate / 5 h / 20 °C

5.1: sodium carbonate / tetrahydrofuran; water / 12 h / 20 °C

6.1: Dess-Martin periodane / dichloromethane / 0.5 h / 20 °C

7.1: 2-methyl-but-2-ene; sodium dihydrogenphosphate dihydrate; sodium chlorite / tetrahydrofuran; tert-butyl alcohol; water / 14 h / 20 °C

8.1: triethylamine; diphenyl phosphoryl azide / dichloromethane / 17.33 h / 0 - 20 °C

9.1: 29 h / Reflux

10.1: potassium carbonate / methanol / 14 h / 20 °C

11.1: triethylamine / dichloromethane / 3 h / 0 - 20 °C

12.1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

With hydrogenchloride; sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; diphenyl phosphoryl azide; diisobutylaluminium hydride; sodium carbonate; potassium carbonate; Dess-Martin periodane; copper(II) sulfate; triethylamine; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane; water; ethyl acetate; toluene; tert-butyl alcohol; 3.1: |Grignard Reaction / 6.1: |Dess-Martin Oxidation / 9.1: |Curtius Rearrangement;

DOI:10.1021/jm400542h

Reference yield:

C27H39NO2SSi (1447825-91-3) → C25H33N3O3 (1447826-05-2)

Guidance literature:

Multi-step reaction with 10 steps

1: tetrahydrofuran; dichloromethane / 0.67 h / 20 °C

2: hydrogenchloride / methanol; ethyl acetate / 5 h / 20 °C

3: sodium carbonate / tetrahydrofuran; water / 12 h / 20 °C

4: Dess-Martin periodane / dichloromethane / 0.5 h / 20 °C

5: 2-methyl-but-2-ene; sodium dihydrogenphosphate dihydrate; sodium chlorite / tetrahydrofuran; tert-butyl alcohol; water / 14 h / 20 °C

6: triethylamine; diphenyl phosphoryl azide / dichloromethane / 17.33 h / 0 - 20 °C

7: 29 h / Reflux

8: potassium carbonate / methanol / 14 h / 20 °C

9: triethylamine / dichloromethane / 3 h / 0 - 20 °C

10: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

With hydrogenchloride; sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; diphenyl phosphoryl azide; sodium carbonate; potassium carbonate; Dess-Martin periodane; triethylamine; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane; water; ethyl acetate; tert-butyl alcohol; 1: |Grignard Reaction / 4: |Dess-Martin Oxidation / 7: |Curtius Rearrangement;

DOI:10.1021/jm400542h

upstream raw materials:

C₃₃H₃₉NO₄Si

C₂₇H₃₉NO₂SSi

C₃₅H₄₉NO₂SSi

C₃₄H₄₀N₂O₄

Downstream raw materials:

C₂₅H₃₇N₃O₄

C₃₆H₄₃N₃O₅

C₃₃H₄₃N₃O₆