N-(2-carboxyphenyl)-exo-7-oxa-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide

Base Information

• Chemical Name: N-(2-carboxyphenyl)-exo-7-oxa-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide
• CAS No.: 493040-01-0
• Molecular Formula: C₁₅H₁₁NO₅
• Molecular Weight: 285.256
• Mol file: 493040-01-0.mol

Synonyms:N-(2-carboxyphenyl)-exo-7-oxa-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide

Chemical Property of N-(2-carboxyphenyl)-exo-7-oxa-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-carboxyphenyl)-exo-7-oxa-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide

There total 4 articles about N-(2-carboxyphenyl)-exo-7-oxa-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride (6118-51-0) + anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4) → N-(2-carboxyphenyl)-exo-7-oxa-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide (493040-01-0)

Guidance literature:

In methanol; at 20 ℃; for 6h; Reflux;

DOI:10.14233/ajchem.2013.15030

Reference yield: 79.0%

C15H13NO6 → N-(2-carboxyphenyl)-exo-7-oxa-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide (493040-01-0)

Guidance literature:

With sodium acetate; acetic anhydride; In N,N-dimethyl-formamide; at 55 ℃; for 5h;

DOI:10.1002/pola.29450

Reference yield:

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride (6118-51-0) → N-(2-carboxyphenyl)-exo-7-oxa-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide (493040-01-0)

Guidance literature:

Multi-step reaction with 2 steps

1: acetonitrile / 5 h / 20 °C

2: acetic anhydride; sodium acetate / N,N-dimethyl-formamide / 5 h / 55 °C

With sodium acetate; acetic anhydride; In N,N-dimethyl-formamide; acetonitrile;

DOI:10.1002/pola.29450

upstream raw materials:

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride

anthranilic acid