5-[3-amino-2-methylpyrazol-4-yl]-3-(4-trifluoromethylphenyl)-1,2,4-triazole

Base Information

Chemical Name:5-[3-amino-2-methylpyrazol-4-yl]-3-(4-trifluoromethylphenyl)-1,2,4-triazole
CAS No.:1345017-73-3
Molecular Formula:C₁₃H₁₁F₃N₆
Molecular Weight:308.266
Hs Code.:

Synonyms:5-[3-amino-2-methylpyrazol-4-yl]-3-(4-trifluoromethylphenyl)-1,2,4-triazole

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Chemical Property of 5-[3-amino-2-methylpyrazol-4-yl]-3-(4-trifluoromethylphenyl)-1,2,4-triazole

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Technology Process of 5-[3-amino-2-methylpyrazol-4-yl]-3-(4-trifluoromethylphenyl)-1,2,4-triazole

There total 12 articles about 5-[3-amino-2-methylpyrazol-4-yl]-3-(4-trifluoromethylphenyl)-1,2,4-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1191274-87-9
8-methyl-2-(4-trifluoromethylphenyl)-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine

: 1345017-73-3
3-[3-amino-2-methylpyrazol-4-yl]-5-(4-trifluoromethylphenyl)-1,2,4-triazole

: 1345017-73-3
5-[3-amino-2-methylpyrazol-4-yl]-3-(4-trifluoromethylphenyl)-1,2,4-triazole

Guidance literature:: 8-methyl-2-(4-trifluoromethylphenyl)-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine; With hydrogenchloride; In water; Reflux;

With ammonium hydroxide; In water;
DOI:10.1016/j.bmc.2011.08.026

Reference yield:

: 1191274-87-9
8-methyl-2-(4-trifluoromethylphenyl)-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine

: 1345017-73-3
3-[3-amino-2-methylpyrazol-4-yl]-5-(4-trifluoromethylphenyl)-1,2,4-triazole

: 1345017-73-3
5-[3-amino-2-methylpyrazol-4-yl]-3-(4-trifluoromethylphenyl)-1,2,4-triazole

Guidance literature:: 8-methyl-2-(4-trifluoromethylphenyl)-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine; With hydrogenchloride; In water; Reflux;

With ammonium hydroxide; In water;
DOI:10.1016/j.bmc.2011.08.026

Reference yield:

: C₁₄H₁₁F₃N₆

: 1345017-73-3
3-[3-amino-2-methylpyrazol-4-yl]-5-(4-trifluoromethylphenyl)-1,2,4-triazole

: 1345017-73-3
5-[3-amino-2-methylpyrazol-4-yl]-3-(4-trifluoromethylphenyl)-1,2,4-triazole

Guidance literature:: Multi-step reaction with 2 steps

1: [bis(acetoxy)iodo]benzene

2: hydrogenchloride / water / Reflux

With hydrogenchloride; [bis(acetoxy)iodo]benzene; In water;
DOI:10.1016/j.bmc.2011.08.026