3,16-dibenzyloxy-4,4,15,15-tetrafluoro-octadeca-1,9E,17-triene-5,14-dione

Base Information

Chemical Name:3,16-dibenzyloxy-4,4,15,15-tetrafluoro-octadeca-1,9E,17-triene-5,14-dione
CAS No.:930286-20-7
Molecular Formula:C₃₂H₃₆F₄O₄
Molecular Weight:560.629
Hs Code.:

Synonyms:3,16-dibenzyloxy-4,4,15,15-tetrafluoro-octadeca-1,9E,17-triene-5,14-dione

Suppliers and Price of 3,16-dibenzyloxy-4,4,15,15-tetrafluoro-octadeca-1,9E,17-triene-5,14-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3,16-dibenzyloxy-4,4,15,15-tetrafluoro-octadeca-1,9E,17-triene-5,14-dione

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3,16-dibenzyloxy-4,4,15,15-tetrafluoro-octadeca-1,9E,17-triene-5,14-dione

There total 6 articles about 3,16-dibenzyloxy-4,4,15,15-tetrafluoro-octadeca-1,9E,17-triene-5,14-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 930286-11-6
3-benzyloxy-4,4-difluoro-deca-1,9-dien-5-one

: 3-benzyloxy-2,2-difluoro-cyclooct-4Z-en-1-one

: 930286-20-7
3,16-dibenzyloxy-4,4,15,15-tetrafluoro-octadeca-1,9E,17-triene-5,14-dione

Guidance literature:: With titanium(IV) isopropylate; Neolyst; In dichloromethane; for 18h; Heating;
DOI:10.1021/jo0620258

Reference yield:

: 914379-40-1
1,1-difluoro-2-(2'-methoxy-ethoxymethoxy)-hepta-1,6-dien-3-ol

: 930286-20-7
3,16-dibenzyloxy-4,4,15,15-tetrafluoro-octadeca-1,9E,17-triene-5,14-dione

Guidance literature:: Multi-step reaction with 5 steps

1: 91 percent / sodium hydroxide; tetra-n-butylammonium hydrogensulfate / H₂O / 16 h / 20 °C

2: 90 percent / lithium diisopropylamide / tetrahydrofuran; hexane / 7.5 h / -100 - -30 °C

3: poly(vinylpyridine); 4-(dimethylamino)pyridine / CH₂Cl₂ / 20 °C

4: 94 percent / thionyl chloride; methanol / 16 h / 0 - 20 °C

5: 38 percent / titanium(iv) isopropoxide / Neolyst / CH₂Cl₂ / 18 h / Heating

With titanium(IV) isopropylate; methanol; dmap; sodium hydroxide; thionyl chloride; poly(vinylpyridine); tetra(n-butyl)ammonium hydrogensulfate; lithium diisopropyl amide; Neolyst; In tetrahydrofuran; hexane; dichloromethane; water; 2: <2,3>-Wittig rearrangement / 5: olefin metathesis;
DOI:10.1021/jo0620258

Reference yield:

: 930285-90-8
3-allyloxy-1,1-difluoro-2-(2'-methoxy-ethoxymethoxy)-hepta-1,6-diene

: 930286-20-7
3,16-dibenzyloxy-4,4,15,15-tetrafluoro-octadeca-1,9E,17-triene-5,14-dione

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / lithium diisopropylamide / tetrahydrofuran; hexane / 7.5 h / -100 - -30 °C

2: poly(vinylpyridine); 4-(dimethylamino)pyridine / CH₂Cl₂ / 20 °C

3: 94 percent / thionyl chloride; methanol / 16 h / 0 - 20 °C

4: 38 percent / titanium(iv) isopropoxide / Neolyst / CH₂Cl₂ / 18 h / Heating

With titanium(IV) isopropylate; methanol; dmap; thionyl chloride; poly(vinylpyridine); lithium diisopropyl amide; Neolyst; In tetrahydrofuran; hexane; dichloromethane; 1: <2,3>-Wittig rearrangement / 4: olefin metathesis;
DOI:10.1021/jo0620258