Adenosine 5'-carboxamide

Base Information

Chemical Name:Adenosine 5'-carboxamide
CAS No.:35788-21-7
Molecular Formula:C₁₀H₁₂N₆O₄
Molecular Weight:280.243
Hs Code.:
DSSTox Substance ID:DTXSID401202089
Nikkaji Number:J48.293E
Wikidata:Q76009732
ChEMBL ID:CHEMBL4778617
Mol file:35788-21-7.mol

Synonyms:adenosine 5'-carboxamide;adenosine 5'-carboxylic acid amide;ADN 5'-CXAAM

Suppliers and Price of Adenosine 5'-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ADENOSINE 5'-CARBOXAMIDE 95.00%
5MG
$ 500.84

Total 13 raw suppliers

Chemical Property of Adenosine 5'-carboxamide

Chemical Property:

Vapor Pressure:4.64E-27mmHg at 25°C
Refractive Index:1.7000 (estimate)
Boiling Point:800.8°Cat760mmHg
Flash Point:438.1°C
PSA：162.40000
Density:2.24g/cm³
LogP:-1.20550
XLogP3:-1.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:2
Exact Mass:280.09200289
Heavy Atom Count:20
Complexity:398

Purity/Quality:

97% ^*data from raw suppliers

ADENOSINE 5'-CARBOXAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)C(=O)N)O)O)N
Isomeric SMILES:C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)C(=O)N)O)O)N

Technology Process of Adenosine 5'-carboxamide

There total 11 articles about Adenosine 5'-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 35788-22-8
2',3'-O-isopropylideneadenosine-5'-carboxamide

: 35788-21-7
adenosine 5'-carboxamide

Guidance literature:: With trifluoroacetic acid; at 0 ℃; for 2h;
DOI:10.1021/jm960313y

Reference yield:

: 19234-66-3
2',3'-isopropylideneadenosine-5'-carboxylic acid

: 35788-21-7
adenosine 5'-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide*HCl / dimethylformamide / 3 h / 20 °C

2: NH₃ / dimethylformamide / 1 h / 20 °C

3: 80percent aq. TFA / 20 °C

With ammonia; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide;
DOI:10.1021/jm000150k

Reference yield:

: 159647-45-7
(3aS,4S,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid 4-nitro-phenyl ester

: 35788-21-7
adenosine 5'-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: NH₃ / dimethylformamide / 1 h / 20 °C

2: 80percent aq. TFA / 20 °C

With ammonia; In N,N-dimethyl-formamide;
DOI:10.1021/jm000150k