2--L-valyl>-L-prolylamido-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-glucose

Base Information

• Chemical Name: 2--L-valyl>-L-prolylamido-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-glucose
• CAS No.: 141280-21-9
• Molecular Formula: C₄₆H₆₁N₅O₁₆
• Molecular Weight: 940.014
• Mol file: 141280-21-9.mol

Synonyms:2--L-valyl>-L-prolylamido-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-glucose

Chemical Property of 2--L-valyl>-L-prolylamido-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-glucose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2--L-valyl>-L-prolylamido-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-glucose

There total 1 articles about 2--L-valyl>-L-prolylamido-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-glucose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3,4,6-tetra-O-acetyl-D-glucosamine hydrochloride (5432-46-2,10034-19-2,10034-20-5,34948-62-4,110253-00-4,1191127-63-5) + -L-valyl>-L-proline (95500-87-1) → 2--L-valyl>-L-prolylamido-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-glucose (141280-21-9)

Guidance literature:

With 4-methyl-morpholine; isobutyl chloroformate; Yield given. Multistep reaction; 1.) THF, -15 deg C, 30 min, 2.) THF, 4 deg C, 15 h;

DOI:10.1016/0223-5234(91)90001-4

Reference yield: 71.0%

2--L-valyl>-L-prolylamido-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-glucose (141280-21-9) → 2--L-valyl>-L-prolylamido-2-deoxy-β-D-glucose (141266-01-5)

Guidance literature:

With sodium methylate; In tetrahydrofuran; methanol; at -10 - 20 ℃; for 0.5h;

DOI:10.1016/0223-5234(91)90001-4

upstream raw materials:

1,3,4,6-tetra-O-acetyl-D-glucosamine hydrochloride

-L-valyl>-L-proline

Downstream raw materials:

2--L-valyl>-L-prolylamido-2-deoxy-β-D-glucose