diethyl 2-acetylamino-2-(2-(4-octanoylphenyl)ethyl)propane-1,3-dioate

Base Information

• Chemical Name: diethyl 2-acetylamino-2-(2-(4-octanoylphenyl)ethyl)propane-1,3-dioate
• CAS No.: 268557-53-5
• Molecular Formula: C₂₅H₃₇NO₆
• Molecular Weight: 447.572
• Mol file: 268557-53-5.mol

Synonyms:diethyl 2-acetylamino-2-(2-(4-octanoylphenyl)ethyl)propane-1,3-dioate

Chemical Property of diethyl 2-acetylamino-2-(2-(4-octanoylphenyl)ethyl)propane-1,3-dioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diethyl 2-acetylamino-2-(2-(4-octanoylphenyl)ethyl)propane-1,3-dioate

There total 7 articles about diethyl 2-acetylamino-2-(2-(4-octanoylphenyl)ethyl)propane-1,3-dioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

4-octanoylstyrene (24993-87-1) + 2-acetylaminomalonic acid diethyl ester (1068-90-2) → diethyl 2-acetylamino-2-(2-(4-octanoylphenyl)ethyl)propane-1,3-dioate (268557-53-5)

Guidance literature:

2-acetylaminomalonic acid diethyl ester; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h; Inert atmosphere;

4-octanoylstyrene; In N,N-dimethyl-formamide; at 20 - 60 ℃; for 30h;

DOI:10.1248/cpb.56.595

Reference yield: 51.0%

4'-(2-iodoethyl)octanophenone (219307-01-4) + 2-acetylaminomalonic acid diethyl ester (1068-90-2) → diethyl 2-acetylamino-2-(2-(4-octanoylphenyl)ethyl)propane-1,3-dioate (268557-53-5) + 4-octanoylstyrene (24993-87-1)

Guidance literature:

2-acetylaminomalonic acid diethyl ester; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Inert atmosphere;

4'-(2-iodoethyl)octanophenone; In N,N-dimethyl-formamide; at 60 ℃; for 2h; Inert atmosphere;

DOI:10.1248/cpb.56.595

Reference yield:

→ diethyl 2-acetylamino-2-(2-(4-octanoylphenyl)ethyl)propane-1,3-dioate (268557-53-5) + 4-octanoylstyrene (24993-87-1)

Guidance literature:

upstream raw materials:

4'-(2-iodoethyl)octanophenone

2-acetylaminomalonic acid diethyl ester

4-octanoylstyrene

1-phenyl-2-bromoethane

Downstream raw materials:

diethyl 2-acetamido-2-[2-(4-octylphenyl)ethyl]malonate