6-[(4-methylphenyl)sulfanyl]-5-nitroso-2,4-pyrimidinediamine

Base Information

• Chemical Name: 6-[(4-methylphenyl)sulfanyl]-5-nitroso-2,4-pyrimidinediamine
• CAS No.: 606964-87-8
• Molecular Formula: C₁₁H₁₁N₅OS
• Molecular Weight: 261.307
• Mol file: 606964-87-8.mol

Synonyms:6-[(4-methylphenyl)sulfanyl]-5-nitroso-2,4-pyrimidinediamine

Chemical Property of 6-[(4-methylphenyl)sulfanyl]-5-nitroso-2,4-pyrimidinediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-[(4-methylphenyl)sulfanyl]-5-nitroso-2,4-pyrimidinediamine

There total 2 articles about 6-[(4-methylphenyl)sulfanyl]-5-nitroso-2,4-pyrimidinediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

6-[(4-methylphenyl)sulfanyl]-2,4-pyrimidinediamine (606964-84-5) → 6-[(4-methylphenyl)sulfanyl]-5-nitroso-2,4-pyrimidinediamine (606964-87-8)

Guidance literature:

With sodium hydroxide; acetic acid; sodium nitrite; In N,N-dimethyl-formamide; at 20 ℃; for 48h;

DOI:10.1039/b300798g

Reference yield:

para-thiocresol (106-45-6) → 6-[(4-methylphenyl)sulfanyl]-5-nitroso-2,4-pyrimidinediamine (606964-87-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / aq. NaOH / ethanol / 80 °C

2: 77 percent / aq. NaOH; NaNO₂; glacial acetic acid / dimethylformamide / 48 h / 20 °C

With sodium hydroxide; acetic acid; sodium nitrite; In ethanol; N,N-dimethyl-formamide;

DOI:10.1039/b300798g

Reference yield: 90.0%

6-[(4-methylphenyl)sulfanyl]-5-nitroso-2,4-pyrimidinediamine (606964-87-8) → 6-[(4-methylphenyl)sulfanyl]-2,4,5-pyrimidinetriamine (606964-88-9)

Guidance literature:

With sodium dithionite; In methanol; at 20 ℃; for 1.5h;

DOI:10.1039/b300798g

upstream raw materials:

6-[(4-methylphenyl)sulfanyl]-2,4-pyrimidinediamine

para-thiocresol

Downstream raw materials:

6-[(4-methylphenyl)sulfanyl]-2,4,5-pyrimidinetriamine

6,7-dimethyl-4-[(4-methylphenyl)sulfanyl]-2-pteridinamine