N-((E)-5-(tert-butyldiphenylsilyloxy)-3-methyl-1-phenylpent-2-enyl)-P,P-diphenylphosphinamide

Base Information

Chemical Name:N-((E)-5-(tert-butyldiphenylsilyloxy)-3-methyl-1-phenylpent-2-enyl)-P,P-diphenylphosphinamide
CAS No.:850089-02-0
Molecular Formula:C₄₀H₄₄NO₂PSi
Molecular Weight:629.854
Hs Code.:

Synonyms:N-((E)-5-(tert-butyldiphenylsilyloxy)-3-methyl-1-phenylpent-2-enyl)-P,P-diphenylphosphinamide

Suppliers and Price of N-((E)-5-(tert-butyldiphenylsilyloxy)-3-methyl-1-phenylpent-2-enyl)-P,P-diphenylphosphinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-((E)-5-(tert-butyldiphenylsilyloxy)-3-methyl-1-phenylpent-2-enyl)-P,P-diphenylphosphinamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-((E)-5-(tert-butyldiphenylsilyloxy)-3-methyl-1-phenylpent-2-enyl)-P,P-diphenylphosphinamide

There total 1 articles about N-((E)-5-(tert-butyldiphenylsilyloxy)-3-methyl-1-phenylpent-2-enyl)-P,P-diphenylphosphinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 98837-46-8,67764-52-7
P,P-diphenyl-N-(phenylmethylene)phosphinic amide

: 75-24-1
trimethylaluminum

: 88158-68-3
4-(tert-butyldiphenylsilyloxy)-1-butyne

: 850089-02-0
N-((E)-5-(tert-butyldiphenylsilyloxy)-3-methyl-1-phenylpent-2-enyl)-P,P-diphenylphosphinamide

Guidance literature:: trimethylaluminum; 4-(tert-butyldiphenylsilyloxy)-1-butyne; With water; zirconocene dichloride; In dichloromethane; at 0 ℃; for 0.666667h;

P,P-diphenyl-N-(phenylmethylene)phosphinic amide; In dichloromethane; at 100 ℃; for 0.125h; microwave irradiation;
DOI:10.1021/ol0501525

Reference yield: 95.0%

: 850089-02-0
N-((E)-5-(tert-butyldiphenylsilyloxy)-3-methyl-1-phenylpent-2-enyl)-P,P-diphenylphosphinamide

: 75-11-6
diiodomethane

: (+/-)-N-(S)-(((1R,2S)-2-(2-(tert-butyldiphenylsilyloxy)ethyl)-2-methylcyclopropyl)(phenyl)methyl)-P,P-diphenylphosphinamide

Guidance literature:: With diethylzinc; In 1,2-dimethoxyethane; dichloromethane; at -20 ℃; for 48h;
DOI:10.1021/ol0501525

Reference yield:

: 850089-02-0
N-((E)-5-(tert-butyldiphenylsilyloxy)-3-methyl-1-phenylpent-2-enyl)-P,P-diphenylphosphinamide

: 850089-26-8
(1R,2R)-2-((S)-Benzyloxycarbonylamino-phenyl-methyl)-1-methyl-cyclopropanecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 8 steps

1.1: 95 percent / Et₂Zn / CH₂Cl₂; 1,2-dimethoxy-ethane / 48 h / -20 °C

2.1: 91 percent / AcOH; TBAF / tetrahydrofuran / 12 °C

3.1: o-NO₂C₆H₄SeCN; Bu₃P / tetrahydrofuran / 1 h / 0 °C

3.2: Na₂HPO₄; m-CPBA / CH₂Cl₂ / -40 °C

3.3: 81 percent / iPr₂NH / CH₂Cl₂ / 12 h / -40 - 20 °C

4.1: NaOH; O₃ / CH₂Cl₂ / 6 h / -78 °C

5.1: 1.3 g / HCl / methanol / 12 h / 0 - 20 °C

6.1: 97 percent / NaHCO₃ / ethyl acetate; H₂O / 2 h / 0 °C

7.1: H₂ / Pd/C / methanol / 2 h / 760 Torr

7.2: 0.63 g / ethanol; H₂O / Heating

8.1: 100 percent / NaHCO₃ / ethyl acetate; H₂O / 2 h / 0 °C

With hydrogenchloride; sodium hydroxide; ortho-nitrophenyl selenocyanate; tributylphosphine; tetrabutyl ammonium fluoride; hydrogen; diethylzinc; sodium hydrogencarbonate; ozone; acetic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; dichloromethane; water; ethyl acetate;
DOI:10.1021/ol0501525