2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]benzenesulfonic acid

Base Information

Chemical Name:2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]benzenesulfonic acid
CAS No.:1228311-65-6
Molecular Formula:C₂₃H₁₈N₄O₄S
Molecular Weight:446.486
Hs Code.:

Synonyms:2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]benzenesulfonic acid

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Chemical Property of 2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]benzenesulfonic acid

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Technology Process of 2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]benzenesulfonic acid

There total 3 articles about 2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]benzenesulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₆H₂₄N₄O₄S

: 1228311-65-6
2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]benzenesulfonic acid

Guidance literature:: With hydrogenchloride; In water;

Reference yield:

: 296759-07-4
C₉H₁₃BO₅S

: 1228311-65-6
2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]benzenesulfonic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / ethanol; water / 1 h / 120 °C / Inert atmosphere

2: hydrogenchloride / water

With hydrogenchloride; potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In ethanol; water;

Reference yield:

: 1101145-49-6
(2-amino-6-iodoquinazolin-4-yl)-(1,3-dihydroisoindol-2-yl)methanone

: 1228311-65-6
2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]benzenesulfonic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / ethanol; water / 1 h / 120 °C / Inert atmosphere

2: hydrogenchloride / water

With hydrogenchloride; potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In ethanol; water;