((2E,4R,5S,7S,8Z,10S,11R,12S,14S,17R,18R,19S,20S,21Z)-19-(4-methoxybenzyloxy)-5,7,11,17-tetrakis(tert-butyldimethylsilanyloxy)-4,10,12,14,18,20-hexamethyltetracosa-2,8,21,23-tetraenyloxy)triphenylmethane

Base Information

• Chemical Name: ((2E,4R,5S,7S,8Z,10S,11R,12S,14S,17R,18R,19S,20S,21Z)-19-(4-methoxybenzyloxy)-5,7,11,17-tetrakis(tert-butyldimethylsilanyloxy)-4,10,12,14,18,20-hexamethyltetracosa-2,8,21,23-tetraenyloxy)triphenylmethane
• CAS No.: 792921-73-4
• Molecular Formula: C₈₁H₁₃₂O₇Si₄
• Molecular Weight: 1330.28
• Mol file: 792921-73-4.mol

Synonyms:((2E,4R,5S,7S,8Z,10S,11R,12S,14S,17R,18R,19S,20S,21Z)-19-(4-methoxybenzyloxy)-5,7,11,17-tetrakis(tert-butyldimethylsilanyloxy)-4,10,12,14,18,20-hexamethyltetracosa-2,8,21,23-tetraenyloxy)triphenylmethane

Chemical Property of ((2E,4R,5S,7S,8Z,10S,11R,12S,14S,17R,18R,19S,20S,21Z)-19-(4-methoxybenzyloxy)-5,7,11,17-tetrakis(tert-butyldimethylsilanyloxy)-4,10,12,14,18,20-hexamethyltetracosa-2,8,21,23-tetraenyloxy)triphenylmethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ((2E,4R,5S,7S,8Z,10S,11R,12S,14S,17R,18R,19S,20S,21Z)-19-(4-methoxybenzyloxy)-5,7,11,17-tetrakis(tert-butyldimethylsilanyloxy)-4,10,12,14,18,20-hexamethyltetracosa-2,8,21,23-tetraenyloxy)triphenylmethane

There total 2 articles about ((2E,4R,5S,7S,8Z,10S,11R,12S,14S,17R,18R,19S,20S,21Z)-19-(4-methoxybenzyloxy)-5,7,11,17-tetrakis(tert-butyldimethylsilanyloxy)-4,10,12,14,18,20-hexamethyltetracosa-2,8,21,23-tetraenyloxy)triphenylmethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C84H142O8Si5 → ((2E,4R,5S,7S,8Z,10S,11R,12S,14S,17R,18R,19S,20S,21Z)-19-(4-methoxybenzyloxy)-5,7,11,17-tetrakis(tert-butyldimethylsilanyloxy)-4,10,12,14,18,20-hexamethyltetracosa-2,8,21,23-tetraenyloxy)triphenylmethane (792921-73-4)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1016/j.tet.2007.05.033

Reference yield:

(13Z,19E)-(2R,3R,4R,5R,8S,10S,11R,12S,15S,17S,18R)-5,11,15,17-Tetrakis-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-2,4,8,10,12,18-hexamethyl-21-trityloxy-henicosa-13,19-dienal + (1-bromoallyl)trimethylsilane (94397-40-7) → ((2E,4R,5S,7S,8Z,10S,11R,12S,14S,17R,18R,19S,20S,21Z)-19-(4-methoxybenzyloxy)-5,7,11,17-tetrakis(tert-butyldimethylsilanyloxy)-4,10,12,14,18,20-hexamethyltetracosa-2,8,21,23-tetraenyloxy)triphenylmethane (792921-73-4)

Guidance literature:

(13Z,19E)-(2R,3R,4R,5R,8S,10S,11R,12S,15S,17S,18R)-5,11,15,17-Tetrakis-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-2,4,8,10,12,18-hexamethyl-21-trityloxy-henicosa-13,19-dienal; (1-bromoallyl)trimethylsilane; With chromium dichloride; In tetrahydrofuran;

With sodium hydride; In tetrahydrofuran;

DOI:10.1002/anie.200460593

Reference yield: 77.0%

((2E,4R,5S,7S,8Z,10S,11R,12S,14S,17R,18R,19S,20S,21Z)-19-(4-methoxybenzyloxy)-5,7,11,17-tetrakis(tert-butyldimethylsilanyloxy)-4,10,12,14,18,20-hexamethyltetracosa-2,8,21,23-tetraenyloxy)triphenylmethane (792921-73-4) → (2E,4R,5S,7S,8Z,10S,11R,12S,14S,17R,18R,19S,20S,21Z)-19-(4-methoxybenzyloxy)-5,7,11,17-tetrakis(tert-butyldimethylsilanyloxy)-4,10,12,14,18,20-hexamethyltetracosa-2,8,21,23-tetraen-1-ol (792921-89-2)

Guidance literature:

With methanol; zinc dibromide; In dichloromethane; at 0 ℃;

DOI:10.1016/j.tet.2007.05.033

upstream raw materials:

(1-bromoallyl)trimethylsilane

Downstream raw materials:

(2E,4R,5S,7S,8Z,10S,11R,12S,14S,17R,18R,19S,20S,21Z)-19-(4-methoxybenzyloxy)-5,7,11,17-tetrakis(tert-butyldimethylsilanyloxy)-4,10,12,14,18,20-hexamethyltetracosa-2,8,21,23-tetraen-1-ol

methyl (2Z,4E,6R,7S,9S,10Z,12S,13R,14S,16S,19R,20R,21S,22S,23Z)-21-(4-methoxybenzyloxy)-7,9,13,19-tetrakis(tert-butyldimethylsilanyloxy)-6,12,14,16,20,22-hexamethylhexacosa-2,4,10,23,25-pentaenoate