4-(chloromethyl)-2-(2,2-dimethylcyclopentyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl

Base Information

Chemical Name:4-(chloromethyl)-2-(2,2-dimethylcyclopentyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl
CAS No.:1253593-82-6
Molecular Formula:C₂₁H₂₄ClFO
Molecular Weight:346.872
Hs Code.:

Synonyms:4-(chloromethyl)-2-(2,2-dimethylcyclopentyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(chloromethyl)-2-(2,2-dimethylcyclopentyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl

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Technology Process of 4-(chloromethyl)-2-(2,2-dimethylcyclopentyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl

There total 1 articles about 4-(chloromethyl)-2-(2,2-dimethylcyclopentyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1142224-51-8
(2-((1R)-2,2-dimethylcyclopentyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methanol

: 1253593-82-6
4-(chloromethyl)-2-(2,2-dimethylcyclopentyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl

Guidance literature:: With thionyl chloride; N,N-dimethyl-formamide; In dichloromethane; at 0 - 20 ℃;

Reference yield: 72.0%

: 1222090-37-0
C₁₄H₁₆O₃

: 1253593-82-6
4-(chloromethyl)-2-(2,2-dimethylcyclopentyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl

: C₃₃H₃₅FO₄

Guidance literature:: C₁₄H₁₆O₃; 4-(chloromethyl)-2-(2,2-dimethylcyclopentyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl; With caesium carbonate; In dimethyl sulfoxide; at 23 ℃; for 16h;

With water; lithium hydroxide; In methanol; dimethyl sulfoxide; at 50 ℃; for 15h;

With hydrogenchloride; In methanol; water; dimethyl sulfoxide;