Technology Process of (2S,3R)-1-tert-Butyldiphenylsilyloxy-2,3-epoxytetradecane
There total 5 articles about (2S,3R)-1-tert-Butyldiphenylsilyloxy-2,3-epoxytetradecane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
diethyl ether;
at -40 ℃;
for 0.25h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / Ambient temperature
2: 1) K2CO3, 2) pyridine / 1) MeOH, 1 h, 0 deg C, 2) Et2O, 30 min, 0 deg C
3: 99 percent / K2CO3 / methanol; tetrahydrofuran / 1 h / 0 °C
4: 100 percent / Et3N, 4-dimethylaminopyridine / CH2Cl2 / 1.5 h / Ambient temperature
5: 75 percent / diethyl ether / 0.25 h / -45 °C
With
pyridine; dmap; potassium carbonate; triethylamine;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane;
DOI:10.1055/s-1992-26290
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 100 percent / Et3N, 4-dimethylaminopyridine / CH2Cl2 / 1.5 h / Ambient temperature
2: 75 percent / diethyl ether / 0.25 h / -45 °C
With
dmap; triethylamine;
In
diethyl ether; dichloromethane;
DOI:10.1055/s-1992-26290
