Technology Process of (4,8-bis-(5-hexylthiophen-2-yl)benzo[1,2-b:4,5-b']dithiophene)
There total 1 articles about (4,8-bis-(5-hexylthiophen-2-yl)benzo[1,2-b:4,5-b']dithiophene) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-hexylthiophene;
With
n-butyllithium;
In
tetrahydrofuran;
at 0 - 50 ℃;
for 0.5h;
Inert atmosphere;
benzo[1,2-b:4,5-b']dithiophene;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
With
hydrogenchloride; tin(II) chloride dihdyrate;
In
tetrahydrofuran;
at 20 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere
1.2: 20 °C / Inert atmosphere
2.1: potassium carbonate; palladium diacetate; tricyclohexylphosphine tetrafluoroborate; Trimethylacetic acid / toluene / 24 h / 100 °C / Inert atmosphere; Schlenk technique
With
n-butyllithium; palladium diacetate; potassium carbonate; tricyclohexylphosphine tetrafluoroborate; Trimethylacetic acid;
In
tetrahydrofuran; hexane; toluene;
DOI:10.1039/c3cc00159h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere
1.2: 20 °C / Inert atmosphere
2.1: potassium carbonate; palladium diacetate; tricyclohexylphosphine tetrafluoroborate; Trimethylacetic acid / toluene / 24 h / 100 °C / Inert atmosphere; Schlenk technique
3.1: piperidine / acetonitrile / 8 h / Inert atmosphere; Reflux
With
piperidine; n-butyllithium; palladium diacetate; potassium carbonate; tricyclohexylphosphine tetrafluoroborate; Trimethylacetic acid;
In
tetrahydrofuran; hexane; toluene; acetonitrile;
3.1: |Knoevenagel Condensation;
DOI:10.1039/c3cc00159h
