3H-Imidazo(4,5-f)quinoxalin-2-amine, 3,5-dimethyl-

Base Information

• Chemical Name: 3H-Imidazo(4,5-f)quinoxalin-2-amine, 3,5-dimethyl-
• CAS No.: 146177-57-3
• Molecular Formula: C₁₁H₁₁N₅
• Molecular Weight: 213.242
• DSSTox Substance ID: DTXSID60163281
• Nikkaji Number: J490.225D
• Wikidata: Q83032165
• Mol file: 146177-57-3.mol

Synonyms:146177-57-3;3H-Imidazo(4,5-f)quinoxalin-2-amine, 3,5-dimethyl-;3,5-dimethylimidazo[4,5-f]quinoxalin-2-amine;2-Amino-3,5-dimethylimidazo(4,5-f)quinoxaline;5-Methyl-IQX;CCRIS 6404;2-AMINO-3,5-DIMETHYLIMIDAZO[4,5-F]QUINOXALINE;3,5-Dimethyl-3H-imidazo(4,5-f)quinoxalin-2-amine;DTXSID60163281

Chemical Property of 3H-Imidazo(4,5-f)quinoxalin-2-amine, 3,5-dimethyl-

Chemical Property:

• Vapor Pressure: 4.18E-09mmHg at 25°C
• Boiling Point: 472.7°Cat760mmHg
• Flash Point: 239.7°C
• PSA: 70.35000
• Density: 1.47g/cm³
• LogP: 1.33720
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 213.10144537
• Heavy Atom Count: 16
• Complexity: 271

Purity/Quality:

2-AMINO-3,5-DIMETHYLIMIDAZO(4,5-F)QUINOXALINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=C(C3=NC=CN=C13)N=C(N2C)N

Technology Process of 3H-Imidazo(4,5-f)quinoxalin-2-amine, 3,5-dimethyl-

There total 4 articles about 3H-Imidazo(4,5-f)quinoxalin-2-amine, 3,5-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-methyl-5-methylamino-4-nitro-2,1,3-benzoselenadiazole (109671-53-6) → 2-amino-3,5-dimethyl-3H-imidazo<4,5-f>quinoxaline (146177-57-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 71 percent / 40percent aq. NH₄SH / methanol / 3 h / Heating

2: 87 percent / 5 M aq. HCl / aq. ethanol / 0.5 h

3: H₂ / Raney nickel / aq. ethanol / 1 h / Ambient temperature

4: aq. ethanol / 5 °C

With hydrogenchloride; ammonium sulfide; hydrogen; nickel; In methanol; ethanol;

Reference yield:

6-methyl-4-methylamino-3-nitro-1,2-benzenediamine (149703-57-1) → 2-amino-3,5-dimethyl-3H-imidazo<4,5-f>quinoxaline (146177-57-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 87 percent / 5 M aq. HCl / aq. ethanol / 0.5 h

2: H₂ / Raney nickel / aq. ethanol / 1 h / Ambient temperature

3: aq. ethanol / 5 °C

With hydrogenchloride; hydrogen; nickel; In ethanol;

Reference yield:

8-methyl-6-methylamino-5-nitroquinoxaline (149703-61-7) → 2-amino-3,5-dimethyl-3H-imidazo<4,5-f>quinoxaline (146177-57-3)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Raney nickel / aq. ethanol / 1 h / Ambient temperature

2: aq. ethanol / 5 °C

With hydrogen; nickel; In ethanol;

upstream raw materials:

bromocyane

7-methyl-5-methylamino-4-nitro-2,1,3-benzoselenadiazole

6-methyl-4-methylamino-3-nitro-1,2-benzenediamine

8-methyl-6-methylamino-5-nitroquinoxaline