2-(2-tetrahydrofuranyl)-5-methanesulfonyl-1-benzenesulfonylindole

Base Information

• Chemical Name: 2-(2-tetrahydrofuranyl)-5-methanesulfonyl-1-benzenesulfonylindole
• CAS No.: 251549-02-7
• Molecular Formula: C₁₉H₁₉NO₅S₂
• Molecular Weight: 405.496
• Mol file: 251549-02-7.mol

Synonyms:2-(2-tetrahydrofuranyl)-5-methanesulfonyl-1-benzenesulfonylindole

Chemical Property of 2-(2-tetrahydrofuranyl)-5-methanesulfonyl-1-benzenesulfonylindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-tetrahydrofuranyl)-5-methanesulfonyl-1-benzenesulfonylindole

There total 2 articles about 2-(2-tetrahydrofuranyl)-5-methanesulfonyl-1-benzenesulfonylindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(±)-2-ethynyltetrahydrofuran (76928-54-6) + 1-benzenesulfonylamino-2-iodo-4-methanesulfonylbenzene (251548-96-6) → 2-(2-tetrahydrofuranyl)-5-methanesulfonyl-1-benzenesulfonylindole (251549-02-7)

Guidance literature:

With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In 1,4-dioxane; at 60 ℃; for 3h;

Reference yield:

(±)-2-ethynyltetrahydrofuran (76928-54-6) + bis(triphenylphosphine)palladium(II) dichloride + 1-benzenesulfonylamino-2-iodo-4-methanesulfonylbenzene (251548-96-6) → 2-(2-tetrahydrofuranyl)-5-methanesulfonyl-1-benzenesulfonylindole (251549-02-7)

Guidance literature:

With copper(I) iodide; triethylamine; In 1,4-dioxane;

upstream raw materials:

(±)-2-ethynyltetrahydrofuran

1-benzenesulfonylamino-2-iodo-4-methanesulfonylbenzene