C₂₅H₂₃IO₂

Base Information

• Chemical Name: C₂₅H₂₃IO₂
• CAS No.: 1257517-86-4
• Molecular Formula: C₂₅H₂₃IO₂
• Molecular Weight: 482.361
• Mol file: 1257517-86-4.mol

Synonyms:C₂₅H₂₃IO₂

Chemical Property of C₂₅H₂₃IO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₂₅H₂₃IO₂

There total 2 articles about C₂₅H₂₃IO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2-Iodophenol (533-58-4) + C19H20O2 (1257517-85-3) → C25H23IO2 (1257517-86-4)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In toluene; at 0 - 20 ℃; optical yield given as %ee;

DOI:10.1039/c0ob00331j

Reference yield:

C19H18O2 (1257517-84-2) → C25H23IO2 (1257517-86-4)

Guidance literature:

Multi-step reaction with 2 steps

1: dimethylsulfide borane complex; (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole / toluene / 2 h / 0 - 20 °C

2: di-isopropyl azodicarboxylate; triphenylphosphine / toluene / 0 - 20 °C

With di-isopropyl azodicarboxylate; dimethylsulfide borane complex; triphenylphosphine; (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole; In toluene; 2: |Mitsunobu Displacement;

DOI:10.1002/cmdc.201300175

Reference yield: 95.0%

C25H23IO2 (1257517-86-4) → C25H22O2 (1257517-87-5)

Guidance literature:

With palladium diacetate; triphenylphosphine; silver carbonate; In toluene; at 80 ℃; for 16h; Microwave irradiation; Inert atmosphere;

DOI:10.1002/cmdc.201300175

upstream raw materials:

2-Iodophenol

C₁₉H₂₀O₂

C₁₉H₁₈O₂

Downstream raw materials:

C₂₅H₂₂O₂