[3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyloxy)-phenyl]-carbamic acid cyclopentyl ester

Base Information

Chemical Name:[3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyloxy)-phenyl]-carbamic acid cyclopentyl ester
CAS No.:127973-98-2
Molecular Formula:C₂₇H₂₈N₂O₇S
Molecular Weight:524.595
Hs Code.:

Synonyms:[3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyloxy)-phenyl]-carbamic acid cyclopentyl ester

Suppliers and Price of [3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyloxy)-phenyl]-carbamic acid cyclopentyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyloxy)-phenyl]-carbamic acid cyclopentyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyloxy)-phenyl]-carbamic acid cyclopentyl ester

There total 7 articles about [3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyloxy)-phenyl]-carbamic acid cyclopentyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 98-10-2
benzenesulfonamide

: 127973-97-1
4-<<3-<<(cyclopentyloxy)carbonyl>amino>phenoxy>methyl>-3-methoxybenzoic acid

: 127973-98-2
[3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyloxy)-phenyl]-carbamic acid cyclopentyl ester

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 48h;
DOI:10.1021/jm00171a043

Reference yield:

: 50715-28-1
cyclopentyl chloroformate

: 127973-98-2
[3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyloxy)-phenyl]-carbamic acid cyclopentyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 2.8 g / 2,6-lutidine / tetrahydrofuran / 3 h / -10 - 25 °C

2: aq. NaOH / tetrahydrofuran; methanol / 1 h / Ambient temperature

3: 82 percent / K₂CO₃ / acetone / 18 h

4: 86 percent / aq. LiOH / tetrahydrofuran; methanol / 4 h

5: 67 percent / 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide hydrochloride, 4-(dimethylamino)pyridine / CH₂Cl₂ / 48 h

With 2,6-dimethylpyridine; dmap; lithium hydroxide; sodium hydroxide; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; methanol; dichloromethane; acetone;
DOI:10.1021/jm00171a043

Reference yield:

: 70264-94-7
methyl 4-(bromomethyl)-3-methoxybenzoate

: 127973-98-2
[3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyloxy)-phenyl]-carbamic acid cyclopentyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / K₂CO₃ / acetone / 18 h

2: 86 percent / aq. LiOH / tetrahydrofuran; methanol / 4 h

3: 67 percent / 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide hydrochloride, 4-(dimethylamino)pyridine / CH₂Cl₂ / 48 h

With dmap; lithium hydroxide; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; methanol; dichloromethane; acetone;
DOI:10.1021/jm00171a043