N-hydroxy-4-[(R)-3-(4-methanesulfonylphenoxy)-1-methylpropyl]piperidine-1-carboxamidine

Base Information

Chemical Name:N-hydroxy-4-[(R)-3-(4-methanesulfonylphenoxy)-1-methylpropyl]piperidine-1-carboxamidine
CAS No.:1204301-96-1
Molecular Formula:C₁₇H₂₇N₃O₄S
Molecular Weight:369.485
Hs Code.:

Synonyms:N-hydroxy-4-[(R)-3-(4-methanesulfonylphenoxy)-1-methylpropyl]piperidine-1-carboxamidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-hydroxy-4-[(R)-3-(4-methanesulfonylphenoxy)-1-methylpropyl]piperidine-1-carboxamidine

Chemical Property:

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Technology Process of N-hydroxy-4-[(R)-3-(4-methanesulfonylphenoxy)-1-methylpropyl]piperidine-1-carboxamidine

There total 1 articles about N-hydroxy-4-[(R)-3-(4-methanesulfonylphenoxy)-1-methylpropyl]piperidine-1-carboxamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1204301-95-0
4-[(R)-3-(4-methanesulfonylphenoxy)-1-methylpropyl]piperidine-1-carbonitrile

: 1204301-96-1
N-hydroxy-4-[(R)-3-(4-methanesulfonylphenoxy)-1-methylpropyl]piperidine-1-carboxamidine

Guidance literature:: With hydroxylamine; In ethanol; water; at 64 ℃; for 1h;

Reference yield:

: 1118-68-9
dimethylaminoacetic acid

: 1204301-96-1
N-hydroxy-4-[(R)-3-(4-methanesulfonylphenoxy)-1-methylpropyl]piperidine-1-carboxamidine

: 1204301-32-5
(3-{4-[(R)-3-(4-methanesulfonylphenoxy)-1-methylpropyl]piperidin-1-yl}-[1,2,4]oxadiazol-5-ylmethyl)dimethylamine

Guidance literature:: dimethylaminoacetic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.25h;

N-hydroxy-4-[(R)-3-(4-methanesulfonylphenoxy)-1-methylpropyl]piperidine-1-carboxamidine; In N,N-dimethyl-formamide; at 20 ℃; for 38h;

Reference yield:

: 1204301-96-1
N-hydroxy-4-[(R)-3-(4-methanesulfonylphenoxy)-1-methylpropyl]piperidine-1-carboxamidine

: 3272-96-6
2-chloro-N-hydroxyethanimidamide

: 1204301-97-2
1-(3-chloromethyl-[1,2,4]oxadiazol-5-yl)-4-[(R)-3-(4-methanesulfonyl-phenoxy)-1-methylpropyl]piperidine

Guidance literature:: N-hydroxy-4-[(R)-3-(4-methanesulfonylphenoxy)-1-methylpropyl]piperidine-1-carboxamidine; 2-chloro-N-hydroxyethanimidamide; With zinc(II) chloride; In diethyl ether; ethyl acetate; at 20 ℃; for 16h;

With hydrogenchloride; In ethanol; at 75 ℃; for 7.5h;

With sodium hydrogencarbonate; In water; pH=7;