C₃₅H₃₂N₄O₃S

Base Information

• Chemical Name: C₃₅H₃₂N₄O₃S
• CAS No.: 1338711-03-7
• Molecular Formula: C₃₅H₃₂N₄O₃S
• Molecular Weight: 588.73
• Mol file: 1338711-03-7.mol

Synonyms:C₃₅H₃₂N₄O₃S

Chemical Property of C₃₅H₃₂N₄O₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₅H₃₂N₄O₃S

There total 15 articles about C₃₅H₃₂N₄O₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

C35H32N6O4S (1338711-04-8) → C35H32N4O3S (1338711-03-7)

Guidance literature:

With triphenylphosphine; In toluene; Reflux;

DOI:10.1021/ol202475r

Reference yield:

C26H21BrN2O3 (1338711-08-2) → C35H32N4O3S (1338711-03-7)

Guidance literature:

Multi-step reaction with 11 steps

1.1: hydrazine hydrate / ethanol / Reflux

2.1: methanol / 24 h / 20 °C

3.1: boron trifluoride diethyl etherate / tetrahydrofuran; dichloromethane / 0.25 h / -40 °C / Inert atmosphere

3.2: 4 h / -40 - 20 °C

4.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere

4.2: 0 °C

5.1: tert.-butyl lithium / diethyl ether; pentane / 1.5 h / -40 - 20 °C / Inert atmosphere

6.1: sodium disulfate / tetrahydrofuran / 5 h / 23 °C

6.2: 3 h

7.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / tetrahydrofuran; water; tert-butyl alcohol / 20 °C

7.2: 2 h / 20 °C

8.1: sodium cyanoborohydride / tetrahydrofuran; acetic acid / 1 h / 0 °C

9.1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

10.1: sodium azide / N,N-dimethyl-formamide / 95 °C

11.1: triphenylphosphine / toluene / Reflux

With osmium(VIII) oxide; sodium azide; sodium disulfate; boron trifluoride diethyl etherate; tert.-butyl lithium; sodium hydride; sodium cyanoborohydride; hydrazine hydrate; 4-methylmorpholine N-oxide; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; water; acetic acid; N,N-dimethyl-formamide; toluene; mineral oil; tert-butyl alcohol; pentane; 11.1: Aza-Wittig reaction;

DOI:10.1021/ol202475r

Reference yield:

tryptamine (61-54-1) → C35H32N4O3S (1338711-03-7)

Guidance literature:

Multi-step reaction with 14 steps

1.1: toluene / Reflux

2.1: pyridinium perbromide hydrobromide / tetrahydrofuran; chloroform / 2.33 h / -10 °C

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 20 °C

3.2: 4 h / 0 - 20 °C

4.1: hydrazine hydrate / ethanol / Reflux

5.1: methanol / 24 h / 20 °C

6.1: boron trifluoride diethyl etherate / tetrahydrofuran; dichloromethane / 0.25 h / -40 °C / Inert atmosphere

6.2: 4 h / -40 - 20 °C

7.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere

7.2: 0 °C

8.1: tert.-butyl lithium / diethyl ether; pentane / 1.5 h / -40 - 20 °C / Inert atmosphere

9.1: sodium disulfate / tetrahydrofuran / 5 h / 23 °C

9.2: 3 h

10.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / tetrahydrofuran; water; tert-butyl alcohol / 20 °C

10.2: 2 h / 20 °C

11.1: sodium cyanoborohydride / tetrahydrofuran; acetic acid / 1 h / 0 °C

12.1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

13.1: sodium azide / N,N-dimethyl-formamide / 95 °C

14.1: triphenylphosphine / toluene / Reflux

With osmium(VIII) oxide; sodium azide; sodium disulfate; pyridinium perbromide hydrobromide; boron trifluoride diethyl etherate; tert.-butyl lithium; sodium hydride; sodium cyanoborohydride; hydrazine hydrate; 4-methylmorpholine N-oxide; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; chloroform; water; acetic acid; N,N-dimethyl-formamide; toluene; mineral oil; tert-butyl alcohol; pentane; 14.1: Aza-Wittig reaction;

DOI:10.1021/ol202475r

upstream raw materials:

tryptamine

C₃₅H₃₁N₃O₅S

C₃₅H₃₃N₃O₅S

C₃₅H₃₂N₆O₄S

Downstream raw materials:

C₂₉H₃₀N₄O