N-<4-benzoyl>-(αS,γS)-γ-fluoroglutamic acid α,γ-di-tert-butyl ester

Base Information

Chemical Name:N-<4-benzoyl>-(αS,γS)-γ-fluoroglutamic acid α,γ-di-tert-butyl ester
CAS No.:173398-30-6
Molecular Formula:C₂₁H₃₁FN₂O₅
Molecular Weight:410.486
Hs Code.:

N-<4-<methylamino>benzoyl>-(αS,γS)-γ-fluoroglutamic acid α,γ-di-tert-butyl ester

Synonyms:N-<4-benzoyl>-(αS,γS)-γ-fluoroglutamic acid α,γ-di-tert-butyl ester

Suppliers and Price of N-<4-benzoyl>-(αS,γS)-γ-fluoroglutamic acid α,γ-di-tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of N-<4-benzoyl>-(αS,γS)-γ-fluoroglutamic acid α,γ-di-tert-butyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of N-<4-benzoyl>-(αS,γS)-γ-fluoroglutamic acid α,γ-di-tert-butyl ester

There total 4 articles about N-<4-benzoyl>-(αS,γS)-γ-fluoroglutamic acid α,γ-di-tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 173315-22-5
N-<4-<<<(benzyloxy)carbonyl>methyl>amino>benzoyl>-(αS,γS)-γ-fluoroglutamic acid α,γ-di-tert-butyl ester

: 173398-30-6
N-<4-benzoyl>-(αS,γS)-γ-fluoroglutamic acid α,γ-di-tert-butyl ester

Guidance literature:: With hydrogen; palladium dihydroxide; In methanol; for 48h; under 2585.7 Torr;
DOI:10.1021/jm950515e

Reference yield:

: 2528-30-5
4-<<(benzyloxy)carbonyl>methylamino>benzoic acid

: 173398-30-6
N-<4-benzoyl>-(αS,γS)-γ-fluoroglutamic acid α,γ-di-tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / DCC, HOBt / dimethylformamide / 60 h / Ambient temperature

2: 99 percent / H₂ / Pd(OH)2 / methanol / 48 h / 2585.7 Torr

With hydrogen; benzotriazol-1-ol; dicyclohexyl-carbodiimide; palladium dihydroxide; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm950515e

Reference yield:

: 32563-25-0,149117-03-3,91383-48-1,91383-47-0
(2S,4S)-L-threo-4-fluoroglutamic acid

: 173398-30-6
N-<4-benzoyl>-(αS,γS)-γ-fluoroglutamic acid α,γ-di-tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / H₂SO₄ / CHCl₃ / 96 h / Ambient temperature

2: 97 percent / DCC, HOBt / dimethylformamide / 60 h / Ambient temperature

3: 99 percent / H₂ / Pd(OH)2 / methanol / 48 h / 2585.7 Torr

With sulfuric acid; hydrogen; benzotriazol-1-ol; dicyclohexyl-carbodiimide; palladium dihydroxide; In methanol; chloroform; N,N-dimethyl-formamide;
DOI:10.1021/jm950515e