(E)-4-Methoxy-4-((Z)-1-methoxy-3-methoxycarbonyl-allyloxy)-but-2-enoic acid methyl ester

Base Information

• Chemical Name: (E)-4-Methoxy-4-((Z)-1-methoxy-3-methoxycarbonyl-allyloxy)-but-2-enoic acid methyl ester
• CAS No.: 130318-68-2
• Molecular Formula: C₁₂H₁₈O₇
• Molecular Weight: 274.271
• Mol file: 130318-68-2.mol

Synonyms:(E)-4-Methoxy-4-((Z)-1-methoxy-3-methoxycarbonyl-allyloxy)-but-2-enoic acid methyl ester

Chemical Property of (E)-4-Methoxy-4-((Z)-1-methoxy-3-methoxycarbonyl-allyloxy)-but-2-enoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (E)-4-Methoxy-4-((Z)-1-methoxy-3-methoxycarbonyl-allyloxy)-but-2-enoic acid methyl ester

There total 1 articles about (E)-4-Methoxy-4-((Z)-1-methoxy-3-methoxycarbonyl-allyloxy)-but-2-enoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Methoxy-(1-methoxy-2-oxo-ethoxy)-acetaldehyde (1035805-68-5) + methyl (triphenylphosphoranylidene)acetate (21204-67-1,2605-67-6) → (E)-4-Methoxy-4-((Z)-1-methoxy-3-methoxycarbonyl-allyloxy)-but-2-enoic acid methyl ester (130318-68-2) + Triphenylphosphine oxide (791-28-6)

Guidance literature:

DOI:10.1016/S0040-4039(00)97588-9

Reference yield:

(E)-4-Methoxy-4-((Z)-1-methoxy-3-methoxycarbonyl-allyloxy)-but-2-enoic acid methyl ester (130318-68-2) → 5-hydroxy-2-(5H)-furanone (14032-66-7) + trans-β-formylacrylic acid (4437-06-3)

Guidance literature:

In 1,4-dioxane; hydrogenchloride; at 100 ℃; for 2h; Yield given. Title compound not separated from byproducts;

DOI:10.1016/S0040-4039(00)97588-9

upstream raw materials:

Methoxy-(1-methoxy-2-oxo-ethoxy)-acetaldehyde

methyl (triphenylphosphoranylidene)acetate

Downstream raw materials:

5-hydroxy-2-(5H)-furanone

trans-β-formylacrylic acid