2-(5-benzyloxy-4-methyl-hex-2-ynoyl)-1-hydroxy-8-isopropoxy-3-methyl-anthraquinone

Base Information

Chemical Name:2-(5-benzyloxy-4-methyl-hex-2-ynoyl)-1-hydroxy-8-isopropoxy-3-methyl-anthraquinone
CAS No.:919114-49-1
Molecular Formula:C₃₂H₃₀O₆
Molecular Weight:510.587
Hs Code.:

Synonyms:2-(5-benzyloxy-4-methyl-hex-2-ynoyl)-1-hydroxy-8-isopropoxy-3-methyl-anthraquinone

Suppliers and Price of 2-(5-benzyloxy-4-methyl-hex-2-ynoyl)-1-hydroxy-8-isopropoxy-3-methyl-anthraquinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(5-benzyloxy-4-methyl-hex-2-ynoyl)-1-hydroxy-8-isopropoxy-3-methyl-anthraquinone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(5-benzyloxy-4-methyl-hex-2-ynoyl)-1-hydroxy-8-isopropoxy-3-methyl-anthraquinone

There total 13 articles about 2-(5-benzyloxy-4-methyl-hex-2-ynoyl)-1-hydroxy-8-isopropoxy-3-methyl-anthraquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 919114-48-0
2-(5-benzyloxy-4-methyl-hex-2-ynoyl)-1,8-diisopropoxy-3-methyl-anthraquinone

: 919114-49-1
2-(5-benzyloxy-4-methyl-hex-2-ynoyl)-1-hydroxy-8-isopropoxy-3-methyl-anthraquinone

Guidance literature:: With sulfuric acid; acetic acid; at 60 ℃; for 0.166667h;
DOI:10.1002/anie.200601992

Reference yield:

: 919114-45-7
5-benzyloxy-4-methyl-hex-2-ynal

: 919114-49-1
2-(5-benzyloxy-4-methyl-hex-2-ynoyl)-1-hydroxy-8-isopropoxy-3-methyl-anthraquinone

Guidance literature:: Multi-step reaction with 4 steps

1.1: n-BuLi / tetrahydrofuran; hexane / -78 °C

1.2: 72 percent / tetrahydrofuran; hexane / 0.17 h / -78 °C

2.1: 90 percent / AgO; HNO₃ / dioxane / 0.5 h / 20 °C

3.1: 97 percent / 2-iodoxybenzoic acid / dimethylsulfoxide; CH₂Cl₂ / 5 h / 20 °C

4.1: 86 percent / H₂SO₄; acetic acid / 0.17 h / 60 °C

With silver(II) oxide; n-butyllithium; sulfuric acid; nitric acid; acetic acid; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; 1,4-dioxane; hexane; dichloromethane; dimethyl sulfoxide;
DOI:10.1002/anie.200601992

Reference yield:

: 919114-35-5
3-bromo-5-isopropoxy-[1,4]-naphthoquinone

: 919114-49-1
2-(5-benzyloxy-4-methyl-hex-2-ynoyl)-1-hydroxy-8-isopropoxy-3-methyl-anthraquinone

Guidance literature:: Multi-step reaction with 9 steps

1.1: benzene / 6 h / 20 °C

2.1: SiO₂ / CH₂Cl₂ / 24 h / 20 °C

3.1: 97 percent / N-bromosuccinimide; iP₂NH / CH₂Cl₂ / 12 h / 20 °C

4.1: 94 percent / Cs₂CO₃ / acetone; dimethylformamide / 12 h / Heating

5.1: 98 percent / Na₂S₂O₄; nBu₄NBr; KOH / H₂O; tetrahydrofuran / 4 h / 20 °C

6.1: n-BuLi / tetrahydrofuran; hexane / -78 °C

6.2: 72 percent / tetrahydrofuran; hexane / 0.17 h / -78 °C

7.1: 90 percent / AgO; HNO₃ / dioxane / 0.5 h / 20 °C

8.1: 97 percent / 2-iodoxybenzoic acid / dimethylsulfoxide; CH₂Cl₂ / 5 h / 20 °C

9.1: 86 percent / H₂SO₄; acetic acid / 0.17 h / 60 °C

With silver(II) oxide; potassium hydroxide; N-Bromosuccinimide; n-butyllithium; sodium dithionite; sulfuric acid; tetrabutylammomium bromide; nitric acid; silica gel; caesium carbonate; acetic acid; diisopropylamine; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; 1,4-dioxane; hexane; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone; benzene;
DOI:10.1002/anie.200601992