Loprazolam mesylate

Base Information

Chemical Name:Loprazolam mesylate
CAS No.:70111-54-5
Molecular Formula:C24H25ClN6O6S
Molecular Weight:561.0099
Hs Code.:
European Community (EC) Number:682-334-2
UNII:VKF8383J65
Wikidata:Q27291872
Mol file:70111-54-5.mol

Synonyms:8-nitro-6-(o-chlorophenyl)-1,2-dihydro-2-(N-methylpiperazin-1-yl)methylene-1H,4H-imidazo (1,2-a)(1,4)benzodiazepin-1-one methanesulfonate;HR 158;HR 458;loprazolam;RU 31158;triazulenone;triazulenone mesylate;triazulenone, (Z)-isomer

Suppliers and Price of Loprazolam mesylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
LOPRAZOLAM MESILATE 95.00%
5MG
$ 505.51

Total 2 raw suppliers

Chemical Property of Loprazolam mesylate

Chemical Property:

Vapor Pressure:3.07E-14mmHg at 25°C
Melting Point:205-210°
Boiling Point:597.5°C at 760 mmHg
Flash Point:315.1°C
PSA：160.08000
LogP:2.85310
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:2
Exact Mass:560.1244814
Heavy Atom Count:38
Complexity:984

Purity/Quality:

97% ^*data from raw suppliers

LOPRAZOLAM MESILATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)C=C2C(=O)N3C(=N2)CN=C(C4=C3C=CC(=C4)[N+](=O)[O-])C5=CC=CC=C5Cl.CS(=O)(=O)O
Isomeric SMILES:CN1CCN(CC1)/C=C\2/C(=O)N3C(=N2)CN=C(C4=C3C=CC(=C4)[N+](=O)[O-])C5=CC=CC=C5Cl.CS(=O)(=O)O
Recent EU Clinical Trials:Self-help program for hypnotics withdrawal in insomniac patients: A randomized controlled clinical trial.
Description Loprazolam mesylate is a potent hypnotic/sedative belonging to the second generation of annulated-l,4-benzodiazepines. The T1/2 of loprazolam (～6 hr.) is longer than those of triazolam and midazolam, but shorter than the “effective” T1/2 of flurazepam.

Technology Process of Loprazolam mesylate

There total 1 articles about Loprazolam mesylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: