(S)-2-methyl-2-propanesulfinic acid [(S)-cyclopropyl-(3-fluorophenyl)methyl]amide

Base Information

Chemical Name:(S)-2-methyl-2-propanesulfinic acid [(S)-cyclopropyl-(3-fluorophenyl)methyl]amide
CAS No.:1075715-49-9
Molecular Formula:C₁₄H₂₀FNOS
Molecular Weight:269.383
Hs Code.:

Synonyms:(S)-2-methyl-2-propanesulfinic acid [(S)-cyclopropyl-(3-fluorophenyl)methyl]amide

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Chemical Property of (S)-2-methyl-2-propanesulfinic acid [(S)-cyclopropyl-(3-fluorophenyl)methyl]amide

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Technology Process of (S)-2-methyl-2-propanesulfinic acid [(S)-cyclopropyl-(3-fluorophenyl)methyl]amide

There total 2 articles about (S)-2-methyl-2-propanesulfinic acid [(S)-cyclopropyl-(3-fluorophenyl)methyl]amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 1073-06-9
3-fluorobromobenzene

: 1075715-48-8
(S)-2-methyl-2-propanesulfinic acid 1-cyclopropylmethylideneamide

: 1075715-49-9
(S)-2-methyl-2-propanesulfinic acid [(S)-cyclopropyl-(3-fluorophenyl)methyl]amide

Guidance literature:: 3-fluorobromobenzene; With magnesium; In tetrahydrofuran; at 50 ℃; for 2h;

(S)-2-methyl-2-propanesulfinic acid 1-cyclopropylmethylideneamide; In tetrahydrofuran; at 50 - 60 ℃; for 2h; Product distribution / selectivity;

Reference yield: 37.5%

: 1073-06-9
3-fluorobromobenzene

: 1075715-48-8
(S)-2-methyl-2-propanesulfinic acid 1-cyclopropylmethylideneamide

: 1075715-50-2
(S)-2-methyl-2-propanesulfinic acid [(R)-cyclopropyl-(3-fluorophenyl)methyl]amide

: 1075715-49-9
(S)-2-methyl-2-propanesulfinic acid [(S)-cyclopropyl-(3-fluorophenyl)methyl]amide

Guidance literature:: 3-fluorobromobenzene; With TurboGrignard; In tetrahydrofuran; at 0 ℃; for 2h;

(S)-2-methyl-2-propanesulfinic acid 1-cyclopropylmethylideneamide; In dichloromethane; at -48 ℃; for 5h; Product distribution / selectivity;