Lanadoxin

Base Information

Chemical Name:Lanadoxin
CAS No.:53735-73-2
Deprecated CAS:11014-58-7
Molecular Formula:C30H44O9
Molecular Weight:548.674
Hs Code.:
DSSTox Substance ID:DTXSID20911508

Synonyms:Lanadoxin;EINECS 258-734-4;Gitaloxigenin-mono-digitoxosid [German];BRN 0070815;Gitaloxigenin-mono-digitoxosid;4-18-00-02466 (Beilstein Handbook Reference);Card-20(22)-enolide, 3-((2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-16-(formyloxy)-14-hydroxy-, (3-beta,5-beta,16-beta)-;(3beta,5beta,16beta)-3-((2,6-Dideoxy-beta-D-ribo-hexopyranosyl)oxy)-14,16-dihydroxycard-20(22)-enolide 16-formate;(3beta,5beta,16beta)-3-[(2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy]-14,16-dihydroxycard-20(22)-enolide 16-formate;DTXSID20911508;Card-20(22)-enolide, 3-((2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-16-(formyloxy)-14-hydroxy-, (3beta,5beta,16beta)-;LS-52375;3-[(2,6-Dideoxyhexopyranosyl)oxy]-16-(formyloxy)-14-hydroxycard-20(22)-enolide;11014-58-7

Suppliers and Price of Lanadoxin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Lanadoxin

Chemical Property:

PSA：131.75000
LogP:3.27270
XLogP3:2.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:5
Exact Mass:548.29853298
Heavy Atom Count:39
Complexity:1010

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(C(CC(O1)OC2CCC3(C(C2)CCC4C3CCC5(C4(CC(C5C6=CC(=O)OC6)OC=O)O)C)C)O)O
Isomeric SMILES:CC1[C@H](C(C[C@@H](O1)O[C@H]2CC[C@]3([C@@H](C2)CCC4C3CC[C@]5([C@@]4(CC([C@@H]5C6=CC(=O)OC6)OC=O)O)C)C)O)O

Technology Process of Lanadoxin

There total 9 articles about Lanadoxin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 23394-07-2
(3β, 5β,14β,16β,17β)-3-<(2,6-dideoxy-3,4-O-(1-methylethylidene)-β-D-ribo-hexopyranosyl)oxy>-14-hydroxy-16-(formyloxy)card-20(22)-enolide

: 53735-73-2
gitoxigenin 16β-formate 3β-digitoxoside

Guidance literature:: With acetic acid; at 22 ℃; for 5h;
DOI:10.1021/jm00156a017

Reference yield:

: 27856-85-5,60873-59-8,70877-96-2
14,16β-dihydroxy-3β-(O⁴-{O⁴-[(R)-1-((R)-1-methyl-2-oxo-ethoxy)-3-oxo-propyl]-β-D-ribo-2,6-dideoxy-hexopyranosyl}-β-D-ribo-2,6-dideoxy-hexopyranosyloxy)-(5β,14β)-card-20(22)-enolide

: 53735-73-2
gitoxigenin 16β-formate 3β-digitoxoside

Guidance literature:: Multi-step reaction with 8 steps

1: NaBH₄ / methanol / 2 h

2: 0.05 N aq. HCl / methanol / 24 h / 22 °C

3: 75 percent / sodium metaperiodate / methanol / 2 h / 22 °C

4: NaBH₄ / methanol / 2 h

5: 0.05 N aq. HCl / methanol / 24 h / 22 °C

6: 72 percent / p-TsOH / 5 h / 22 °C

7: 80 percent / pyridine / 2 h / 0 - 5 °C

8: 67 percent / 60percent aq. HOAc / 5 h / 22 °C

With pyridine; hydrogenchloride; sodium tetrahydroborate; sodium periodate; toluene-4-sulfonic acid; acetic acid; In methanol;
DOI:10.1021/jm00156a017

Reference yield:

: C₃₅H₅₆O₁₁

: 53735-73-2
gitoxigenin 16β-formate 3β-digitoxoside

Guidance literature:: Multi-step reaction with 4 steps

1: 0.05 N aq. HCl / methanol / 24 h / 22 °C

2: 72 percent / p-TsOH / 5 h / 22 °C

3: 80 percent / pyridine / 2 h / 0 - 5 °C

4: 67 percent / 60percent aq. HOAc / 5 h / 22 °C

With pyridine; hydrogenchloride; toluene-4-sulfonic acid; acetic acid; In methanol;
DOI:10.1021/jm00156a017