2-Dibenzofuranamine

Base Information

• Chemical Name: 2-Dibenzofuranamine
• CAS No.: 3693-22-9
• Molecular Formula: C12H9 N O
• Molecular Weight: 183.21
• Hs Code.: 2932999099
• European Community (EC) Number: 836-089-5
• NSC Number: 402280
• UNII: 008JZJ6NVX
• DSSTox Substance ID: DTXSID4039239
• Nikkaji Number: J34.846E
• Wikidata: Q27231336
• ChEMBL ID: CHEMBL1449551
• Mol file: 3693-22-9.mol

Synonyms:2-DIBENZOFURANAMINE;3693-22-9;Dibenzo[b,d]furan-2-amine;2-Aminodibenzofuran;dibenzofuran-2-amine;2-Aminodiphenylene oxide;2-Ado;NSC 402280;UNII-008JZJ6NVX;BRN 0142223;008JZJ6NVX;NSC-402280;5-18-10-00061 (Beilstein Handbook Reference);Nc1ccc2Oc3ccccc3c2c1;MLS000389369;SCHEMBL257005;Dibenzo[b,d]furan-2-amine #;CHEMBL1449551;DTXSID4039239;ETHANOLAMINEN,O-DISTEARATE;WLN: T B656 HOJ DZ;HMS1783O01;HMS2539E09;AMINODIPHENYLENE OXIDE, 2-;MFCD00033416;NSC402280;AKOS000200663;LS-7193;NCGC00246066-01;DS-10120;SMR000255642;CS-0036033;D5494;FT-0661715;EN300-33935;W10066;A913840;Q27231336;Z56904747;8-oxatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-amine

Chemical Property of 2-Dibenzofuranamine

Chemical Property:

• Vapor Pressure: 1.21E-05mmHg at 25°C
• Melting Point: 128°C
• Refractive Index: 1.5880 (estimate)
• Boiling Point: 369.1°Cat760mmHg
• PKA: 3.91±0.30(Predicted)
• Flash Point: 177°C
• PSA: 39.16000
• Density: 1.283g/cm³
• LogP: 3.74940
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 183.068413911
• Heavy Atom Count: 14
• Complexity: 218

Purity/Quality:

99% ^*data from raw suppliers

2-Aminodibenzofuran ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=C(O2)C=CC(=C3)N
• Uses: 2-Aminodibenzofuran is a polycyclic aromatic hydrocarbon (PAH) used in the preparation of mono and bisazo dyes. 2-Aminodibenzofuran is a carcinogen.

Technology Process of 2-Dibenzofuranamine

There total 13 articles about 2-Dibenzofuranamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-acetyldibenzofuran (13761-32-5) → dibenzo[b,d]furan-2-amine (3693-22-9)

Guidance literature:

With methanol; O-benzenesulfonyl-acetohydroxamic acid ethyl ester; toluene-4-sulfonic acid; at 23 ℃; for 24h; Inert atmosphere;

DOI:10.1021/acs.orglett.9b00807

Reference yield: 77.0%

LiC12H7O (51498-17-0) → dibenzo[b,d]furan-2-amine (3693-22-9)

Guidance literature:

LiC₁₂H₇O; With copper(I) chloride bis(lithium chloride) complex; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;

With 3,3’-di-tert-butyl oxaziridine; In tetrahydrofuran; at -78 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1021/jacs.6b12712

Reference yield: 72.0%

2-nitrodibenzofuran (20927-95-1) → dibenzo[b,d]furan-2-amine (3693-22-9)

Guidance literature:

With hydrazine hydrate; nickel; In ethanol; Heating;

DOI:10.1002/prac.19983400505

upstream raw materials:

2-bromodibenzo[b,d]furan

2-iododibenzofuran

2-nitrodibenzofuran

5-amino-2'-chloro-biphenyl-2-ol

Downstream raw materials:

N-dibenzofuran-2-yl-acetamide

2-bromodibenzo[b,d]furan

2-hydroxydibenzofuran

N-([1,1‘-biphenyl]-4-yl)dibenzo[b,d]furan-2-amine

Refernces

• 1、 -. "AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS". Paragraph 0098; 0142; 0143; 0222; 0257. . Retrieved 2018/03/25.
• 2、 -. "An electroluminescent compound and an electroluminescent device comprising the same". Paragraph 0415; 0422-0427; 0699; 0706-0711. . Retrieved 2020/09/12.