alpha-D-Glucose 1,6-bisphosphate

Base Information

• Chemical Name: alpha-D-Glucose 1,6-bisphosphate
• CAS No.: 10139-18-1
• Deprecated CAS: 28472-37-9,29315-85-3,28983-35-9
• Molecular Formula: C6H14 O12 P2
• Molecular Weight: 340.117
• European Community (EC) Number: 233-395-5
• UNII: DRX17R6AM2
• DSSTox Substance ID: DTXSID801014547
• Nikkaji Number: J40.064E
• Wikipedia: Glucose_1,6-bisphosphate
• Wikidata: Q4122197
• Metabolomics Workbench ID: 38350
• Mol file: 10139-18-1.mol

Synonyms:beta-D-glucose 1,6-(bis)phosphate;glucose 1,6-diphosphate;glucose-1,6-bisphosphate;glucose-1,6-diphosphate

Chemical Property of alpha-D-Glucose 1,6-bisphosphate

Chemical Property:

• Boiling Point: 733.2°Cat760mmHg
• PKA: 1.73±0.10(Predicted)
• Flash Point: 397.2°C
• PSA: 223.06000
• Density: 2.05g/cm³
• LogP: -2.98740
• XLogP3: -5.3
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 5
• Exact Mass: 339.99604987
• Heavy Atom Count: 20
• Complexity: 414

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C1C(C(C(C(O1)OP(=O)(O)O)O)O)O)OP(=O)(O)O
• Isomeric SMILES: C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)OP(=O)(O)O)O)O)O)OP(=O)(O)O

Technology Process of alpha-D-Glucose 1,6-bisphosphate

There total 5 articles about alpha-D-Glucose 1,6-bisphosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ glucosee 1,6-diphosphate (10139-18-1,19456-00-9,19504-70-2,22933-98-8,29834-61-5,52795-15-0,136376-94-8,136376-95-9,136376-98-2,136376-99-3,136377-01-0,136377-03-2,136377-05-4,136377-06-5,136377-09-8,136377-10-1,136377-12-3,136377-15-6,136377-16-7,305-58-8)

Guidance literature:

1,2,3,6-Tetra-O-acetyl-6-O-phosphono-β-D-glucopyranose: 1) H3PO4 2) LiOH;

Reference yield:

1,2,3,4-tetra-O-acetyl-β-D-glucopyranose 6-diphenylphosphate (108321-48-8) → 6-phospho-α-D-glucopyranosyl-1-phosphate (10139-18-1)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid; hydrogen bromide

2: benzene / Hydrieren des Reaktionsprodukts an Platin in Methanol und Behandeln der Reaktionsloesung mit wss. Natronlauge

With hydrogen bromide; acetic acid; benzene;

Reference yield:

O2,O3,O4-triacetyl-O6-diphenoxyphosphoryl-α-D-glucopyranosyl bromide (102112-80-1) → β-D-glucose-6-phosphate-1-phosphorane (52795-15-0) + 6-phospho-α-D-glucopyranosyl-1-phosphate (10139-18-1)

Guidance literature:

With silver orthophosphate; benzene; Hydrieren des Reaktionsprodukts an Platin in Methanol und Behandeln der Reaktionsloesung mit konz. wss. Salzsaeure und anschliessend mit wss. Natronlauge;

upstream raw materials:

O²,O³,O⁴-triacetyl-O⁶-diphenoxyphosphoryl-α-D-glucopyranosyl bromide

1,2,3,4-tetra-O-acetyl-β-D-glucopyranose 6-diphenylphosphate

Downstream raw materials:

glucose 1-phosphate

glucose-6-phosphate

O¹,O⁵-Diphosphono-α-D-ribofuranose