2,4-dichloro-5-[(2-fluorophenyl)sulfamoyl]benzoic Acid

Base Information

Chemical Name:2,4-dichloro-5-[(2-fluorophenyl)sulfamoyl]benzoic Acid
CAS No.:329265-50-1
Molecular Formula:C₁₃H₈Cl₂FNO₄S
Molecular Weight:364.181
Hs Code.:
DSSTox Substance ID:DTXSID901183648

Synonyms:2,4-dichloro-5-[(2-fluorophenyl)sulfamoyl]benzoic Acid;329265-50-1;2,4-Dichloro-5-[[(2-fluorophenyl)amino]sulfonyl]benzoic acid;2,4-dichloro-5-{[(2-fluorophenyl)amino]sulfonyl}benzoic acid;2,4-Dichloro-5-(2-fluoro-phenylsulfamoyl)-benzoic acid;SCHEMBL398219;VCKGEUQEYFBEPU-UHFFFAOYSA-N;DTXSID901183648;AKOS000114760;CS-0218243;EN300-00448;SR-01000029507;SR-01000029507-1;Z45639793;2,4-dichloro-5-[(2-fluorophenyl)sulfamoyl]benzoicAcid

Suppliers and Price of 2,4-dichloro-5-[(2-fluorophenyl)sulfamoyl]benzoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2,4-dichloro-5-[(2-fluorophenyl)sulfamoyl]benzoic Acid

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:362.9535125
Heavy Atom Count:22
Complexity:513

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)NS(=O)(=O)C2=C(C=C(C(=C2)C(=O)O)Cl)Cl)F

Technology Process of 2,4-dichloro-5-[(2-fluorophenyl)sulfamoyl]benzoic Acid

There total 2 articles about 2,4-dichloro-5-[(2-fluorophenyl)sulfamoyl]benzoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1235560-79-8
ethyl 2,4-dichloro-5-{[(2-fluorophenyl)amino]sulfonyl}benzoate

: 329265-50-1
2,4-dichloro-5-{[(2-fluorophenyl)amino]sulfonyl}benzoic acid

Guidance literature:: ethyl 2,4-dichloro-5-{[(2-fluorophenyl)amino]sulfonyl}benzoate; With water; sodium hydroxide; In ethanol; at 20 ℃; for 0.75h;

With hydrogenchloride; In ethanol; water;

Reference yield:

: 348-54-9
2-Fluoroaniline

: 3740-18-9
2,4-dichloro-5-(chlorosulfonyl)benzoic acid

: 329265-50-1
2,4-dichloro-5-{[(2-fluorophenyl)amino]sulfonyl}benzoic acid

Guidance literature:: In acetone; Reflux;
DOI:10.2174/1573406414666180924164327

Reference yield:

: 329265-50-1
2,4-dichloro-5-{[(2-fluorophenyl)amino]sulfonyl}benzoic acid

: 96193-27-0
(8aR)-1,2,3,4,6,7,8,8a-octahydropyrrolo[1,2-a]pyrazine

: 1235560-78-7
(R)-2,4-dichloro-N-(2-fluorophenyl)-5-(octahydropyrrolo[1,2-a]pyrazine-2-carbonyl)benzenesulfonamide

Guidance literature:: 2,4-dichloro-5-{[(2-fluorophenyl)amino]sulfonyl}benzoic acid; (8aR)-1,2,3,4,6,7,8,8a-octahydropyrrolo[1,2-a]pyrazine; With HATU; In 2-methyltetrahydrofuran; ISOPROPYLAMIDE; at 20 ℃; for 4h;

With sodium hydrogencarbonate; In 2-methyltetrahydrofuran; ISOPROPYLAMIDE;