6-phenylthieno[2,3-d]pyrimidine-2,4-dicarboxylate diethyl ester

Base Information

• Chemical Name: 6-phenylthieno[2,3-d]pyrimidine-2,4-dicarboxylate diethyl ester
• CAS No.: 1162684-76-5
• Molecular Formula: C₁₈H₁₆N₂O₄S
• Molecular Weight: 356.402
• Mol file: 1162684-76-5.mol

Synonyms:6-phenylthieno[2,3-d]pyrimidine-2,4-dicarboxylate diethyl ester

Chemical Property of 6-phenylthieno[2,3-d]pyrimidine-2,4-dicarboxylate diethyl ester

Chemical Property:

Purity/Quality:

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Technology Process of 6-phenylthieno[2,3-d]pyrimidine-2,4-dicarboxylate diethyl ester

There total 1 articles about 6-phenylthieno[2,3-d]pyrimidine-2,4-dicarboxylate diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

2-amino-5-phenylthiophene-3-carboxylic acid (14770-84-4) + triethyl 1,3,5-triazine-2,4,6-tricarboxylate (898-22-6) → 6-phenylthieno[2,3-d]pyrimidine-2,4-dicarboxylate diethyl ester (1162684-76-5)

Guidance literature:

In acetic acid; N,N-dimethyl-formamide; at 80 ℃; regioselective reaction; Inert atmosphere;

DOI:10.1016/j.tetlet.2009.03.180

upstream raw materials:

2-amino-5-phenylthiophene-3-carboxylic acid

triethyl 1,3,5-triazine-2,4,6-tricarboxylate