bis[4-(ethyl-2-(acetoxyethyl)aminocarbonyl)-benzyl]trithiocarbonate

Base Information

• Chemical Name: bis[4-(ethyl-2-(acetoxyethyl)aminocarbonyl)-benzyl]trithiocarbonate
• CAS No.: 948877-08-5
• Molecular Formula: C₂₉H₃₆N₂O₆S₃
• Molecular Weight: 604.813
• Mol file: 948877-08-5.mol

Synonyms:bis[4-(ethyl-2-(acetoxyethyl)aminocarbonyl)-benzyl]trithiocarbonate

Chemical Property of bis[4-(ethyl-2-(acetoxyethyl)aminocarbonyl)-benzyl]trithiocarbonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis[4-(ethyl-2-(acetoxyethyl)aminocarbonyl)-benzyl]trithiocarbonate

There total 3 articles about bis[4-(ethyl-2-(acetoxyethyl)aminocarbonyl)-benzyl]trithiocarbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

carbon disulfide (75-15-0,12122-00-8) + N-ethyl-N-(2-acetoxyethyl)-4-(chloromethyl)benzamide (948877-07-4) → bis[4-(ethyl-2-(acetoxyethyl)aminocarbonyl)-benzyl]trithiocarbonate (948877-08-5)

Guidance literature:

carbon disulfide; With potassium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 0.25h;

N-ethyl-N-(2-acetoxyethyl)-4-(chloromethyl)benzamide; In N,N-dimethyl-formamide; at 50 ℃; for 24h;

DOI:10.1002/pola.26380

Reference yield:

N-ethyl-N-(2-hydroxyethyl)-4-(chloromethyl)benzamide (948877-06-3) → bis[4-(ethyl-2-(acetoxyethyl)aminocarbonyl)-benzyl]trithiocarbonate (948877-08-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: dmap; triethylamine / toluene / 2 h / 20 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 0.25 h / 50 °C

2.2: 24 h / 50 °C

With dmap; potassium carbonate; triethylamine; In N,N-dimethyl-formamide; toluene;

DOI:10.1002/pola.26380

Reference yield:

p-(chloromethyl)benzoyl chloride (876-08-4) → bis[4-(ethyl-2-(acetoxyethyl)aminocarbonyl)-benzyl]trithiocarbonate (948877-08-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: tetrahydrofuran / 4 h / 0 - 20 °C

2.1: dmap; triethylamine / toluene / 2 h / 20 °C

3.1: potassium carbonate / N,N-dimethyl-formamide / 0.25 h / 50 °C

3.2: 24 h / 50 °C

With dmap; potassium carbonate; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide; toluene;

DOI:10.1002/pola.26380

upstream raw materials:

p-(chloromethyl)benzoyl chloride

N-ethyl-N-(2-hydroxyethyl)-4-(chloromethyl)benzamide

carbon disulfide

N-ethyl-N-(2-acetoxyethyl)-4-(chloromethyl)benzamide

Downstream raw materials:

bis[4-(ethyl-2-(hydroxyethyl)aminocarbonyl)-benzyl]trithiocarbonate

Refernces