tert-butyl allyl(4-allyl-1-benzyl-1H-pyrazol-5-yl)carbamate

Base Information

• Chemical Name: tert-butyl allyl(4-allyl-1-benzyl-1H-pyrazol-5-yl)carbamate
• CAS No.: 1421698-62-5
• Molecular Formula: C₂₁H₂₇N₃O₂
• Molecular Weight: 353.464
• Mol file: 1421698-62-5.mol

Synonyms:tert-butyl allyl(4-allyl-1-benzyl-1H-pyrazol-5-yl)carbamate

Chemical Property of tert-butyl allyl(4-allyl-1-benzyl-1H-pyrazol-5-yl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl allyl(4-allyl-1-benzyl-1H-pyrazol-5-yl)carbamate

There total 4 articles about tert-butyl allyl(4-allyl-1-benzyl-1H-pyrazol-5-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

C18H23N3O2 + allyl bromide (106-95-6) → tert-butyl allyl(4-allyl-1-benzyl-1H-pyrazol-5-yl)carbamate (1421698-62-5)

Guidance literature:

C₁₈H₂₃N₃O₂; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 0.5h;

allyl bromide; In tetrahydrofuran; for 1h;

DOI:10.1016/j.tetlet.2012.12.042

Reference yield:

C13H15N3 (1421698-86-3) → tert-butyl allyl(4-allyl-1-benzyl-1H-pyrazol-5-yl)carbamate (1421698-62-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: dmap / tetrahydrofuran / 20 °C

2.1: sodium hydride / tetrahydrofuran / 0.5 h / 20 °C

2.2: 1 h

With dmap; sodium hydride; In tetrahydrofuran;

DOI:10.1016/j.tetlet.2012.12.042

Reference yield:

4-Pentenenitrile (592-51-8) → tert-butyl allyl(4-allyl-1-benzyl-1H-pyrazol-5-yl)carbamate (1421698-62-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.25 h / -78 °C

1.2: 0.5 h

2.1: ethanol / 1 h / 20 °C

3.1: dmap / tetrahydrofuran / 20 °C

4.1: sodium hydride / tetrahydrofuran / 0.5 h / 20 °C

4.2: 1 h

With dmap; sodium hexamethyldisilazane; sodium hydride; In tetrahydrofuran; ethanol;

DOI:10.1016/j.tetlet.2012.12.042

upstream raw materials:

C₁₃H₁₅N₃

allyl bromide

4-Pentenenitrile