N-(2-pyridinyl)-N'-(4-methoxyphenyl)-S-phenyl-S-methyl sulfondiimine

Base Information

• Chemical Name: N-(2-pyridinyl)-N'-(4-methoxyphenyl)-S-phenyl-S-methyl sulfondiimine
• CAS No.: 1438414-43-7
• Molecular Formula: C₁₉H₁₉N₃OS
• Molecular Weight: 337.445
• Mol file: 1438414-43-7.mol

Synonyms:N-(2-pyridinyl)-N'-(4-methoxyphenyl)-S-phenyl-S-methyl sulfondiimine

Chemical Property of N-(2-pyridinyl)-N'-(4-methoxyphenyl)-S-phenyl-S-methyl sulfondiimine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-pyridinyl)-N'-(4-methoxyphenyl)-S-phenyl-S-methyl sulfondiimine

There total 3 articles about N-(2-pyridinyl)-N'-(4-methoxyphenyl)-S-phenyl-S-methyl sulfondiimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-bromo-pyridine (109-04-6) + N-H-N-(4-methoxyphenyl)-S-phenyl-S-methyl sulfondiimine (1378302-81-8) → N-(2-pyridinyl)-N'-(4-methoxyphenyl)-S-phenyl-S-methyl sulfondiimine (1438414-43-7)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; ruphos; In toluene; at 110 ℃; for 20h;

DOI:10.1002/adsc.201200754

Reference yield:

aniline (62-53-3) → N-(2-pyridinyl)-N'-(4-methoxyphenyl)-S-phenyl-S-methyl sulfondiimine (1438414-43-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium carbonate; N-chloro-succinimide / N,N-dimethyl-formamide / 0.25 h / 0 °C / Inert atmosphere

1.2: 12 h / 20 °C / Inert atmosphere

2.1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; ruphos; caesium carbonate / toluene / 20 h / 110 °C

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-chloro-succinimide; sodium carbonate; caesium carbonate; ruphos; In N,N-dimethyl-formamide; toluene;

DOI:10.1002/adsc.201200754

Reference yield:

S-methyl-S-phenyl sulfiliminium mesitylenesulfonate → N-(2-pyridinyl)-N'-(4-methoxyphenyl)-S-phenyl-S-methyl sulfondiimine (1438414-43-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium carbonate; N-chloro-succinimide / N,N-dimethyl-formamide / 0.25 h / 0 °C / Inert atmosphere

1.2: 12 h / 20 °C / Inert atmosphere

2.1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; ruphos; caesium carbonate / toluene / 20 h / 110 °C

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-chloro-succinimide; sodium carbonate; caesium carbonate; ruphos; In N,N-dimethyl-formamide; toluene;

DOI:10.1002/adsc.201200754

upstream raw materials:

2-bromo-pyridine

N-H-N-(4-methoxyphenyl)-S-phenyl-S-methyl sulfondiimine

aniline

Downstream raw materials:

C₁₂H₁₃N₃S