N-[(S)-N-benzyloxycarbonylphenylglycyl]sarcosine ethyl ester

Base Information

• Chemical Name: N-[(S)-N-benzyloxycarbonylphenylglycyl]sarcosine ethyl ester
• CAS No.: 931115-09-2
• Molecular Formula: C₂₁H₂₄N₂O₅
• Molecular Weight: 384.432
• Mol file: 931115-09-2.mol

Synonyms:N-[(S)-N-benzyloxycarbonylphenylglycyl]sarcosine ethyl ester

Chemical Property of N-[(S)-N-benzyloxycarbonylphenylglycyl]sarcosine ethyl ester

Chemical Property:

Purity/Quality:

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Technology Process of N-[(S)-N-benzyloxycarbonylphenylglycyl]sarcosine ethyl ester

There total 1 articles about N-[(S)-N-benzyloxycarbonylphenylglycyl]sarcosine ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.4%

sarcosine ethyl ester hydrochloride (52605-49-9) + (S)-N-(benzyloxycarbonyl)phenylglycine (5491-18-9,17609-52-8,53990-33-3,60584-76-1) → N-[(S)-N-benzyloxycarbonylphenylglycyl]sarcosine ethyl ester (931115-09-2)

Guidance literature:

(S)-N-(benzyloxycarbonyl)phenylglycine; With chloroformic acid ethyl ester; triethylamine; In dichloromethane; at -10 ℃; for 0.166667h;

sarcosine ethyl ester hydrochloride; With triethylamine; In dichloromethane; at -10 - 0 ℃; for 0.75h;

Reference yield: 88.0%

N-[(S)-N-benzyloxycarbonylphenylglycyl]sarcosine ethyl ester (931115-09-2) → (S)-1-methyl-3-phenylpiperazine-2,5-dione (931115-07-0)

Guidance literature:

With hydrogen; acetic acid; 5%-palladium/activated carbon; for 2h; under 3677.86 Torr; Product distribution / selectivity;

upstream raw materials:

sarcosine ethyl ester hydrochloride

(S)-N-(benzyloxycarbonyl)phenylglycine

Downstream raw materials:

(S)-1-methyl-3-phenylpiperazine-2,5-dione