Pentanoic acid, 2-propyl-, hydrazide

Base Information

• Chemical Name: Pentanoic acid, 2-propyl-, hydrazide
• CAS No.: 22632-36-6
• Molecular Formula: C8H18 N2 O
• Molecular Weight: 158.244
• Hs Code.: 2928000090
• Mol file: 22632-36-6.mol

Synonyms:Valericacid, 2-propyl-, hydrazide (8CI); Dipropylacetohydrazide

Chemical Property of Pentanoic acid, 2-propyl-, hydrazide

Chemical Property:

• Vapor Pressure: 0.00162mmHg at 25°C
• Boiling Point: 294.5°C at 760 mmHg
• Flash Point: 131.9°C
• PSA: 58.61000
• Density: 0.927g/cm³
• LogP: 2.73330

Purity/Quality:

2-PROPYLPENTANEHYDRAZIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pentanoic acid, 2-propyl-, hydrazide

There total 4 articles about Pentanoic acid, 2-propyl-, hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

N'-(2-Propyl-pentanoyl)-hydrazinecarboxylic acid tert-butyl ester → valproic hydrazide (22632-36-6)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/S0960-894X(97)00005-X

Reference yield: 85.0%

valproic acid (99-66-1) → valproic hydrazide (22632-36-6)

Guidance literature:

valproic acid; In ethanol; for 12h; Acidic conditions; Reflux;

With hydrazine; In ethanol; for 12h; Reflux;

DOI:10.3390/molecules200814638

Reference yield: 68.0%

methyl 2-propylvalerate (22632-59-3) → valproic hydrazide (22632-36-6)

Guidance literature:

With hydrazine hydrate; In ethanol; at 110 ℃;

DOI:10.1002/ddr.21851

upstream raw materials:

methyl 2-propylvalerate

valproyl chloride

valproic acid

Downstream raw materials:

N'-Cyclohexylidendipropylacetohydrazid

N'-Isopropylidendipropylacetohydrazid

N'-(4-chlorobenzylidene)-2-propylpentanehydrazide