(3S,4R)-4-(4-Ethoxy-3-nitro-phenyl)-7-methoxy-2,2-dimethyl-3-phenyl-chroman

Base Information

Chemical Name:(3S,4R)-4-(4-Ethoxy-3-nitro-phenyl)-7-methoxy-2,2-dimethyl-3-phenyl-chroman
CAS No.:78838-27-4
Molecular Formula:C₂₆H₂₇NO₅
Molecular Weight:433.504
Hs Code.:

Synonyms:(3S,4R)-4-(4-Ethoxy-3-nitro-phenyl)-7-methoxy-2,2-dimethyl-3-phenyl-chroman

Suppliers and Price of (3S,4R)-4-(4-Ethoxy-3-nitro-phenyl)-7-methoxy-2,2-dimethyl-3-phenyl-chroman

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3S,4R)-4-(4-Ethoxy-3-nitro-phenyl)-7-methoxy-2,2-dimethyl-3-phenyl-chroman

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Technology Process of (3S,4R)-4-(4-Ethoxy-3-nitro-phenyl)-7-methoxy-2,2-dimethyl-3-phenyl-chroman

There total 2 articles about (3S,4R)-4-(4-Ethoxy-3-nitro-phenyl)-7-methoxy-2,2-dimethyl-3-phenyl-chroman which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 78838-23-0,78838-24-1
3,4-cis-7-Methoxy-2,2-dimethyl-3-phenyl-4-(4'-hydroxy-3'-nitrophenyl)chroman

: 78838-27-4
(3S,4R)-4-(4-Ethoxy-3-nitro-phenyl)-7-methoxy-2,2-dimethyl-3-phenyl-chroman

Guidance literature:: With potassium carbonate; In acetone; Heating;

Reference yield:

: 51423-18-8
cis-2,2-Dimethyl-3-phenyl-4-(p-hydroxyphenyl)-7-methoxychroman

: 78838-27-4
(3S,4R)-4-(4-Ethoxy-3-nitro-phenyl)-7-methoxy-2,2-dimethyl-3-phenyl-chroman

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / conc. HNO₃ / acetic acid / 0.5 h / 8 - 10 °C

2: 70 percent / K₂CO₃ / acetone / Heating

With nitric acid; potassium carbonate; In acetic acid; acetone;