<<3aR-(3aα,4α,5α,6α,6aα)>-N-(5-Benzyloxy-4-benzyloxymethyl-4,6-dihydroxy-3a,5,6,6a-tetrahydro-4H-cyclopentoxazol-2-yl)>-2,3,4,6-tetra-O-benzyl-α-D-glucopyranosylamine

Base Information

• Chemical Name: <<3aR-(3aα,4α,5α,6α,6aα)>-N-(5-Benzyloxy-4-benzyloxymethyl-4,6-dihydroxy-3a,5,6,6a-tetrahydro-4H-cyclopentoxazol-2-yl)>-2,3,4,6-tetra-O-benzyl-α-D-glucopyranosylamine
• CAS No.: 159517-72-3
• Molecular Formula: C₅₅H₅₈N₂O₁₀
• Molecular Weight: 907.073

Synonyms:<<3aR-(3aα,4α,5α,6α,6aα)>-N-(5-Benzyloxy-4-benzyloxymethyl-4,6-dihydroxy-3a,5,6,6a-tetrahydro-4H-cyclopentoxazol-2-yl)>-2,3,4,6-tetra-O-benzyl-α-D-glucopyranosylamine

Chemical Property of <<3aR-(3aα,4α,5α,6α,6aα)>-N-(5-Benzyloxy-4-benzyloxymethyl-4,6-dihydroxy-3a,5,6,6a-tetrahydro-4H-cyclopentoxazol-2-yl)>-2,3,4,6-tetra-O-benzyl-α-D-glucopyranosylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <<3aR-(3aα,4α,5α,6α,6aα)>-N-(5-Benzyloxy-4-benzyloxymethyl-4,6-dihydroxy-3a,5,6,6a-tetrahydro-4H-cyclopentoxazol-2-yl)>-2,3,4,6-tetra-O-benzyl-α-D-glucopyranosylamine

There total 5 articles about <<3aR-(3aα,4α,5α,6α,6aα)>-N-(5-Benzyloxy-4-benzyloxymethyl-4,6-dihydroxy-3a,5,6,6a-tetrahydro-4H-cyclopentoxazol-2-yl)>-2,3,4,6-tetra-O-benzyl-α-D-glucopyranosylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

N-(2,3,4,6-Tetra-O-benzyl-1-deoxy-α-D-glucopyranosyl)-N'-<<1R-(1α,2α,3α,4β,5β)>-2-benzyloxy-1-benzyloxymethyl-1,3,4-trihydroxycyclopentan-5-yl>thiourea (159517-71-2) → <<3aR-(3aα,4α,5α,6α,6aα)>-N-(5-Benzyloxy-4-benzyloxymethyl-4,6-dihydroxy-3a,5,6,6a-tetrahydro-4H-cyclopentoxazol-2-yl)>-2,3,4,6-tetra-O-benzyl-α-D-glucopyranosylamine (159517-72-3)

Guidance literature:

With 3-ethyl-2-chlorobenzoxazolium tetrafluoroborate; In acetonitrile; at 0 ℃; for 1h;

DOI:10.7164/antibiotics.47.932

Reference yield:

2,3,4,6-Tetra-O-benzyl-α-D-glucopyranosyl isothiocyanate (93173-26-3) → <<3aR-(3aα,4α,5α,6α,6aα)>-N-(5-Benzyloxy-4-benzyloxymethyl-4,6-dihydroxy-3a,5,6,6a-tetrahydro-4H-cyclopentoxazol-2-yl)>-2,3,4,6-tetra-O-benzyl-α-D-glucopyranosylamine (159517-72-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / Et₃N / tetrahydrofuran / 1.) 0 deg C, 5 min, 2.) r.t., 21 h

2: 71 percent / 2-chloro-3-ethylbenzoxazolium tetrafluoroborate / acetonitrile / 1 h / 0 °C

With 3-ethyl-2-chlorobenzoxazolium tetrafluoroborate; triethylamine; In tetrahydrofuran; acetonitrile;

DOI:10.7164/antibiotics.47.932

Reference yield:

(1R,2S,3R,4R,5R)-3-Amino-5-benzyloxy-4-benzyloxymethyl-cyclopentane-1,2,4-triol → <<3aR-(3aα,4α,5α,6α,6aα)>-N-(5-Benzyloxy-4-benzyloxymethyl-4,6-dihydroxy-3a,5,6,6a-tetrahydro-4H-cyclopentoxazol-2-yl)>-2,3,4,6-tetra-O-benzyl-α-D-glucopyranosylamine (159517-72-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / Et₃N / tetrahydrofuran / 1.) 0 deg C, 5 min, 2.) r.t., 21 h

2: 71 percent / 2-chloro-3-ethylbenzoxazolium tetrafluoroborate / acetonitrile / 1 h / 0 °C

With 3-ethyl-2-chlorobenzoxazolium tetrafluoroborate; triethylamine; In tetrahydrofuran; acetonitrile;

DOI:10.7164/antibiotics.47.932

upstream raw materials:

N-(2,3,4,6-Tetra-O-benzyl-1-deoxy-α-D-glucopyranosyl)-N'-<<1R-(1α,2α,3α,4β,5β)>-2-benzyloxy-1-benzyloxymethyl-1,3,4-trihydroxycyclopentan-5-yl>thiourea

2,3,4,6-Tetra-O-benzyl-α-D-glucopyranosyl isothiocyanate

(1R,2R,3S,4R,5R)-2-Amino-5-benzyloxy-1-benzyloxymethyl-3,4-bis-methoxymethoxy-cyclopentanol

<1R-(1α,2α,3α,4β,5β)>-5-Azido-2-benzyloxy-1-benzyloxymethyl-3,4-di(methoxymethoxy)-1-cyclopentanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 159517-72-3 <<3aR-(3aα,4α,5α,6α,6aα)>-N-(5-Benzyloxy-4-benzyloxymethyl-4,6-dihydroxy-3a,5,6,6a-tetrahydro-4H-cyclopentoxazol-2-yl)>-2,3,4,6-tetra-O-benzyl-α-D-glucopyranosylamine

Send

Send

Metric Ton KG G Pound L ML

Send

Send