3-methyl-4-oxopent-2-en-2-yl prop-2-ynyl carbonate

Base Information

• Chemical Name: 3-methyl-4-oxopent-2-en-2-yl prop-2-ynyl carbonate
• CAS No.: 1446518-33-7
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.203
• Mol file: 1446518-33-7.mol

Synonyms:3-methyl-4-oxopent-2-en-2-yl prop-2-ynyl carbonate

Chemical Property of 3-methyl-4-oxopent-2-en-2-yl prop-2-ynyl carbonate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 3-methyl-4-oxopent-2-en-2-yl prop-2-ynyl carbonate

There total 1 articles about 3-methyl-4-oxopent-2-en-2-yl prop-2-ynyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propargyl chloroformate (35718-08-2) + 3-Methyl-2,4-pentanedione (815-57-6) → 3-methyl-4-oxopent-2-en-2-yl prop-2-ynyl carbonate (1446518-33-7) + prop-2-ynyl 2-acetyl-2-methyl-3-oxobutanoate (1446518-34-8)

Guidance literature:

3-Methyl-2,4-pentanedione; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.166667h; Inert atmosphere;

propargyl chloroformate; In tetrahydrofuran; at 20 ℃; for 1h; Overall yield = 62 %; Overall yield = 209 mg; Inert atmosphere;

DOI:10.1021/ol401729m

Reference yield: 85.0%

2-acetylcyclohexanone (874-23-7,125117-37-5) + 3-methyl-4-oxopent-2-en-2-yl prop-2-ynyl carbonate (1446518-33-7) → 3-(3-(1-acetyl-2-oxocyclohexyl)prop-1-en-2-yl)-3-methylpentane-2,4-dione

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; xantphos; In 1,4-dioxane; at 80 ℃; for 2h; Inert atmosphere; Sealed tube;

DOI:10.1055/s-0036-1591957

Reference yield: 73.0%

3-benzyl-pentane-2,4-dione (1134-87-8) + 3-methyl-4-oxopent-2-en-2-yl prop-2-ynyl carbonate (1446518-33-7) → 3,6-diacetyl-6-benzyl-3-methyl-4-methyleneoctane-2,7-dione

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; xantphos; In 1,4-dioxane; at 80 ℃; for 2h; Inert atmosphere; Sealed tube;

DOI:10.1055/s-0036-1591957

upstream raw materials:

propargyl chloroformate

3-Methyl-2,4-pentanedione

Downstream raw materials:

3-methyl-3-(3-phenoxyprop-1-en-2-yl)pentane-2,4-dione