(R)-N-(4-methoxybenzyl)-6-oxo-2,2-bis(trifluoromethyl)-1,3-dioxane-4-carboxamide

Base Information

Chemical Name:(R)-N-(4-methoxybenzyl)-6-oxo-2,2-bis(trifluoromethyl)-1,3-dioxane-4-carboxamide
CAS No.:1017239-39-2
Molecular Formula:C₁₅H₁₃F₆NO₅
Molecular Weight:401.262
Hs Code.:

Synonyms:(R)-N-(4-methoxybenzyl)-6-oxo-2,2-bis(trifluoromethyl)-1,3-dioxane-4-carboxamide

Suppliers and Price of (R)-N-(4-methoxybenzyl)-6-oxo-2,2-bis(trifluoromethyl)-1,3-dioxane-4-carboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-N-(4-methoxybenzyl)-6-oxo-2,2-bis(trifluoromethyl)-1,3-dioxane-4-carboxamide

Chemical Property:

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Technology Process of (R)-N-(4-methoxybenzyl)-6-oxo-2,2-bis(trifluoromethyl)-1,3-dioxane-4-carboxamide

There total 1 articles about (R)-N-(4-methoxybenzyl)-6-oxo-2,2-bis(trifluoromethyl)-1,3-dioxane-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₅H₁₅F₆NO₆

: 1017239-39-2
(R)-N-(4-methoxybenzyl)-6-oxo-2,2-bis(trifluoromethyl)-1,3-dioxane-4-carboxamide

Guidance literature:: With diisopropyl-carbodiimide; In dichloromethane; for 1h;
DOI:10.1021/jo7025788

Reference yield: 87.0%

: 1017239-39-2
(R)-N-(4-methoxybenzyl)-6-oxo-2,2-bis(trifluoromethyl)-1,3-dioxane-4-carboxamide

: 5241-58-7
L-Phenylalanine amide

: 1017239-43-8
C₂₁H₂₅N₃O₅

Guidance literature:: In acetone; at 20 ℃; for 12h;
DOI:10.1021/jo7025788

Reference yield:

: 1017239-39-2
(R)-N-(4-methoxybenzyl)-6-oxo-2,2-bis(trifluoromethyl)-1,3-dioxane-4-carboxamide

: 70626-37-8
9-fluorenylmethyloxycarbonyl-L-leucine anhydride

: 1017239-49-4
C₄₂H₄₆N₄O₈

Guidance literature:: (R)-N-(4-methoxybenzyl)-6-oxo-2,2-bis(trifluoromethyl)-1,3-dioxane-4-carboxamide; H-Phe-NH-Rink amide-MBHA-resin; In 1,4-dioxane;

9-fluorenylmethyloxycarbonyl-L-leucine anhydride; With dmap; for 3h;

With trifluoroacetic acid; In water; for 1h; Further stages.;
DOI:10.1021/jo7025788