C₂₇H₃₆O₄

Base Information

• Chemical Name: C₂₇H₃₆O₄
• CAS No.: 1192233-25-2
• Molecular Formula: C₂₇H₃₆O₄
• Molecular Weight: 424.58
• Mol file: 1192233-25-2.mol

Synonyms:C₂₇H₃₆O₄

Chemical Property of C₂₇H₃₆O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₃₆O₄

There total 14 articles about C₂₇H₃₆O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

C59H72O4Si2 → C27H36O4 (1192233-25-2)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; acetic acid; at 20 ℃; for 10h; Inert atmosphere;

DOI:10.1021/jo401799f

Reference yield:

C27H34O4 (1192233-24-1) → C27H36O4 (1192233-25-2)

Guidance literature:

C₂₇H₃₄O₄; With sodium tris(acetoxy)borohydride; In benzene; at 25 ℃; Inert atmosphere;

With water; ammonium chloride; In benzene; Saturated solution;

DOI:10.1002/anie.200903382

Reference yield:

tert-butyl(((1R,2R,5R)-2-(2-methoxyvinyl)-5-methylcyclohexyl)methoxy)dimethylsilane → C27H36O4 (1192233-25-2)

Guidance literature:

Multi-step reaction with 13 steps

1.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / water; acetone / 5 h / 0 °C / Inert atmosphere

2.1: dichloromethane / 12 h / 20 °C / Inert atmosphere

3.1: methyllithium / tetrahydrofuran; diethyl ether / 0.17 h / -78 °C / Inert atmosphere

3.2: 0.25 h / -78 - 0 °C / Inert atmosphere

4.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydride / tetrahydrofuran; mineral oil / Inert atmosphere

5.1: acetic acid / tetrahydrofuran; water / 12 h / 20 °C / Inert atmosphere

6.1: Dess-Martin periodane / dichloromethane / 0.33 h / 20 °C / Inert atmosphere

7.1: chromium dichloride / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere; Glovebox

8.1: dichloro bis(acetonitrile) palladium(II) / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere

9.1: water; m-xylene / 3 h / 160 °C / Inert atmosphere

10.1: diisobutylaluminium hydride / toluene / 0.67 h / -78 - 0 °C / Inert atmosphere

11.1: 1H-imidazole / dichloromethane / 0.42 h / 20 °C / Inert atmosphere

12.1: Dess-Martin periodane / dichloromethane / 0.5 h / 20 °C / Inert atmosphere

13.1: tetrabutyl ammonium fluoride / tetrahydrofuran; acetic acid / 10 h / 20 °C / Inert atmosphere

With 1H-imidazole; chromium dichloride; dichloro bis(acetonitrile) palladium(II); osmium(VIII) oxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutyl ammonium fluoride; methyllithium; sodium hydride; diisobutylaluminium hydride; Dess-Martin periodane; acetic acid; 4-methylmorpholine N-oxide; In tetrahydrofuran; diethyl ether; dichloromethane; water; acetic acid; N,N-dimethyl-formamide; m-xylene; acetone; toluene; mineral oil; 2.1: |Wittig Olefination / 8.1: |Stille Cross Coupling;

DOI:10.1021/jo401799f

upstream raw materials:

C₂₇H₃₄O₄

Downstream raw materials:

C₂₉H₃₇IO₃S